Osteopontin (OPN), a secreted phosphoprotein, is a member of the small integrin-binding
ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many …

Biomineralization of skeletal components (eg, bone and teeth) is generally accepted to
occur under strict cellular regulation, leading to mineral–organic composites with …

Microcalcifications, primarily biogenic apatite, occur in cancerous and benign breast
pathologies and are key mammographic indicators. Outside the clinic, numerous …

Breast microcalcifications are a common mammographic finding. Microcalcifications are
considered suspicious signs of breast cancer and a breast biopsy is required, however …

Aberrant lipid accumulation and marked changes in cellular lipid profiles are related to
breast cancer metabolism and disease progression. In vitro, these phenomena are primarily …

Microcalcifications play an important role in cancer detection. They are evaluated by their
radiological and histological characteristics but it is challenging to find a link between their …

Mineral particles that form in soft tissues in association with disease conditions are
heterogeneous in their composition and physiochemical properties. Hence, it is challenging …

Obesity increases the risk and worsens the prognosis for breast cancer due, in part, to
altered adipose stromal cell (ASC) behavior. Whether ASCs from obese individuals increase …

Microcalcifications are important diagnostic indicators of disease in breast tissue. Tissue
microenvironments differ in many aspects between normal and cancerous cells, notably …

Scanning transmission X-ray microscopy (STXM) provides the imaging of biological
specimens allowing the parallel collection of localized spectroscopic information by X-ray …