Four decades of progress in cylindrospermopsin research: The ins and outs of a potent cyanotoxin

Y Yang, G Yu, Y Chen, N Jia, R Li - Journal of hazardous materials, 2021 - Elsevier
The cyanotoxin cylindrospermopsin (CYN), a toxic metabolite from cyanobacteria, is of
particular concern due to its cosmopolitan occurrence, aquatic bioaccumulation, and multi …

Global scanning of cylindrospermopsin: Critical review and analysis of aquatic occurrence, bioaccumulation, toxicity and health hazards

KR Scarlett, S Kim, LM Lovin, S Chatterjee… - Science of The Total …, 2020 - Elsevier
Cylindrospermopsin (CYN), a cyanotoxin produced by harmful algal blooms, has been
reported worldwide; however, there remains limited understanding of its potential risks to …

In Vitro Toxicological Assessment of Cylindrospermopsin: A Review

S Pichardo, AM Cameán, A Jos - Toxins, 2017 - mdpi.com
Cylindrospermopsin (CYN) is a cyanobacterial toxin that is gaining importance, owing to its
increasing expansion worldwide and the increased frequency of its blooms. CYN mainly …

Immunotoxic effects induced by microcystins and cylindrospermopsin: A review

L Diez-Quijada, MM Benítez-González, M Puerto, A Jos… - Toxins, 2021 - mdpi.com
Cyanotoxin occurrence is gaining importance due to anthropogenic activities, climate
change and eutrophication. Among them, Microcystins (MCs) and Cylindrospermopsin …

Aphanizomenon gracile (Nostocales), a cylindrospermopsin-producing cyanobacterium in Polish lakes

M Kokociński, J Mankiewicz-Boczek, T Jurczak… - … Science and Pollution …, 2013 - Springer
The cyanobacterial cytotoxin cylindrospermopsin (CYN) has become increasingly common
in fresh waters worldwide. It was originally isolated from Cylindrospermopsis raciborskii in …

Cylindrospermopsin: Water-linked potential threat to human health in Europe

B Poniedziałek, P Rzymski, M Kokociński - Environmental Toxicology and …, 2012 - Elsevier
Cylindrospermopsin (CYN) is a secondary metabolite produced by several cyanobacteria
species. Its potential effect on human health includes liver, kidneys, lungs, spleen and …

Mutagenic and genotoxic potential of pure Cylindrospermopsin by a battery of in vitro tests

M Puerto, AI Prieto, S Maisanaba… - Food and chemical …, 2018 - Elsevier
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide
occurrence. The main route of human exposure is through the ingestion of contaminated …

Subchronic oral cylindrospermopsin exposure alters the host gut microbiome and is associated with progressive hepatic inflammation, stellate cell activation, and mild …

P Saha, M Upright, D Bose, S Roy, A Trivedi, M More… - Toxins, 2022 - mdpi.com
Epidemiological studies have reported a strong association between liver injury and
incidences of hepatocellular carcinoma in sections of humans globally. Several preclinical …

First Report of Cylindrospermopsin Production by Two Cyanobacteria (Dolichospermum mendotae and Chrysosporum ovalisporum) in Lake Iznik, Turkey

R Akcaalan, L Köker, A Oğuz, L Spoof, J Meriluoto… - Toxins, 2014 - mdpi.com
Cylindrospermopsin (CYN) is a cytotoxic alkaloid produced by cyanobacteria. The
distribution of this toxin is expanding around the world and the number of cyanobacteria …

Genotoxic potential of the binary mixture of cyanotoxins microcystin-LR and cylindrospermopsin

K Hercog, S Maisanaba, M Filipič, Á Jos, AM Cameán… - Chemosphere, 2017 - Elsevier
Increased eutrophication of water bodies promotes cyanobacterial blooming that is
hazardous due to the production of various bioactive compounds. Microcystin-LR (MCLR) is …