Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and
community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic …

Aloe emodin-conjugated sulfonyl hydrazones were designed and synthesized as novel type
of antibacterial modulators. Aloe emodin benzenesulfonyl hydrazone 5a (AEBH-5a) was …

Invasive fungal infections (IFIs) are increasing as major infectious diseases around the
world, and the limited efficacy of existing medications has resulted in substantial morbidity …

Fourteen novel Schiff base compounds (AS‐1∼ AS‐14) containing 5‐amino‐1H‐1, 2, 4‐
triazole‐3‐carboxylic acid and substituted benzaldehyde were successfully synthesized …

Hybrid molecules have become a well-established and powerful biologically relevant
heterocycles. They constitute a core structure due to their widespread use in pharmaceutical …

The emergence of drug-resistant bacterial strains continues to be one of the major
challenges of medicine. For this reason, the importance of searching for novel structures of …

This review provides a comprehensive overview of research on 1, 2, 4‐triazoles conducted
over the last fifteen years. 1, 2, 4‐Triazoles are highly significant in the pharmaceutical …

Tuberculosis is a deadly communicable disease caused by the bacillus Mycobacterium
tuberculosis (MTB), and pulmonary tuberculosis accounts for over 80% of the total cases …

Abstract Since 2011 Direct Acting antivirals (DAAs) drugs targeting different non-structural
(NS) viral proteins (NS3, NS5A or NS5B inhibitors) have been approved for clinical use in …