Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …

The WNT/β-catenin is among one of the most extensively studied cellular signaling
pathways involved in the initiation and progression of several deadly cancers. It is now …

Abstract Type IIA topoisomerase (TOP2A) is significantly associated with malignant tumor
development, invasion, treatment and its prognosis, and has been shown to be a therapeutic …

The duck Tembusu virus (DTMUV) is a mosquito-borne flavivirus. It causes severe
symptoms of egg-drop, as well as neurological symptoms and brain damage in ducks …

Abstract DNA topoisomerase II alpha (TOP2A) expression, gene alterations, and enzyme
activity have been studied in various malignant tumors. Abnormal elevation of TOP2A …

Quiescent cancer cells are major impediments to effective radiotherapy (RT) and exhibit
limited sensitivity to traditional photon therapy. Herein, the functional role and underlying …

How ACE2 functions as the major host receptor of SARS-CoV-2 despite having low
expression in the lungs is still unknown. To facilitate the development of therapeutic …

Cinnamaldehyde (CA) is a natural compound that has promising biological activity. The
current study investigates the antitumor activity of CA in thioacetamide induced …

Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common
cancer worldwide, which accounts for approximately 6% of all cases and is responsible for …

Background: Diabetes mellitus (DM) is a prevalent chronic disease that is becoming
increasingly common worldwide and can lead to a number of dangerous complications. The …