Background More than 90% of the adult population globally is chronically infected by the
Epstein–Barr virus (EBV). It is well established that EBV is associated with a number of …

year net survival of children and adolescents diagnosed with cancer is approximately 80%
in many high-income countries. This estimate is encouraging as it shows the substantial …

Epstein–Barr virus (EBV), originally discovered through its association with Burkitt
lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative …

MYC regulates a complex biological program by transcriptionally activating and repressing
its numerous target genes. As such, MYC is a master regulator of many processes, including …

The COVID‐19 pandemic is one of the most serious global challenges to delivering
affordable and equitable treatment to children with cancer we have witnessed in the last few …

Aberrant gene silencing is highly associated with altered cell cycle regulation during
carcinogenesis. In particular, silencing of the CDKN2A tumor suppressor gene, which …

Advances in the treatment of childhood cancers have resulted in part from the development
of national and international collaborative initiatives that have defined biologic determinants …

Currently, there is no effective treatment for Burkitt's lymphoma in patients aged above 60
years, and thus research on effective treatment options for Burkitt's lymphoma has been …

Background: Noncommunicable diseases, and especially cancers, are recognized as an
increasing problem for low and middle income countries. Effective control programs require …

Burkitt lymphoma (BL) is a highly aggressive, B-cell, non-Hodgkin lymphoma categorized
into endemic, sporadic, and immunodeficiency-associated subtypes. BL has distinct …