Heavy metals and metalloid exposure are among the most common factors responsible for
reproductive toxicity in human beings. Several studies have indicated that numerous metals …

The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …

Accumulating evidence demonstrates that ferroptosis may be important in the
pathophysiological process of traumatic brain injury (TBI). As a major hormone of the pineal …

The glucagon-like peptide 1 receptor (GLP1R) is a major drug target with several agonists
being prescribed in individuals with type 2 diabetes and obesity,. The impact of genetic …

Steroid‐induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific
mechanism remains unclear. Glucocorticoid (GC‐)‐induced death of osteoblasts and bone …

Coronaviruses (CoVs) are a group of single stranded RNA viruses, of which some of them
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …

The presence of signaling-competent G protein-coupled receptors in intracellular
compartments is increasingly recognized. Recently, the presence of G i/o protein-coupled …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic (DA) neurons and aggregation of α‐synuclein (α‐syn). Ferroptosis, a form of …

Abstract Melatonin (5‐methoxy‐N‐acetyltryptamine) binds with high affinity and specificity to
membrane receptors. Several receptor subtypes exist in different species, of which the …

Melatonin is a bioamine produced primarily in the pineal gland, although peripheral sites,
including the gut, may also be its minor source. Melatonin regulates various functions …