Progress in mesenchymal stem cell therapy for ischemic stroke

Y Guo, Y Peng, H Zeng, G Chen - Stem cells international, 2021 - Wiley Online Library
Ischemic stroke (IS) is a serious cerebrovascular disease with high morbidity and disability
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …

Overcoming the Blood–Brain Barrier: Multifunctional Nanomaterial‐Based Strategies for Targeted Drug Delivery in Neurological Disorders

CD McLoughlin, S Nevins, JB Stein, M Khakbiz… - Small …, 2024 - Wiley Online Library
The development of effective therapies for neurological disorders is a growing area of
research due to the increasing prevalence of these conditions. Some neurological disorders …

Gold nanoparticles in neurological diseases: A review of neuroprotection

MC Chiang, YP Yang, CJB Nicol, CJ Wang - International Journal of …, 2024 - mdpi.com
This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological
diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and …

Stem cell interventions in neurology: From bench to bedside

MA Pappolla, P Wu, X Fang… - Journal of …, 2024 - journals.sagepub.com
Stem cell therapies are progressively redefining the treatment landscape for a spectrum of
neurological and age-related disorders. This review discusses the molecular and functional …

Mesenchymal stem cells and their extracellular vesicles as emerging therapeutic tools in the treatment of ischemic stroke

DIN Pratiwi, S Alhajlah, A Alawadi, A Hjazi, T Alawsi… - Tissue and Cell, 2024 - Elsevier
Ischemic stroke (IS) is a neurological condition characterized by severe long-term
consequences and an unfavorable prognosis for numerous patients. Despite advancements …

Nanoparticles in combating neuronal dysregulated signaling pathways: Recent approaches to the nanoformulations of phytochemicals and synthetic drugs against …

S Fakhri, S Abdian, SN Zarneshan… - International journal …, 2022 - Taylor & Francis
As the worldwide average life expectancy has grown, the prevalence of age-related
neurodegenerative diseases (NDDs) has risen dramatically. A progressive loss of neuronal …

Modafinil exerts anticonvulsive effects against lithium-pilocarpine-induced status epilepticus in rats: A role for tumor necrosis factor-α and nitric oxide signaling

F Moradi, F Eslami, N Rahimi, A Koohfar, M Shayan… - Epilepsy & Behavior, 2022 - Elsevier
Background Status epilepticus (SE) is a continuous episode of seizures which leads to
hippocampal neurodegeneration, severe systemic inflammation, and extreme damage to the …

Revolutionizing Stroke Care: Nanotechnology-Based Brain Delivery as a Novel Paradigm for Treatment and Diagnosis

PG Balaji, LS Bhimrao, AK Yadav - Molecular Neurobiology, 2024 - Springer
Stroke, a severe medical condition arising from abnormalities in the coagulation-fibrinolysis
cycle and metabolic processes, results in brain cell impairment and injury due to blood flow …

Controlled Drug Release Systems for Cerebrovascular Diseases

C Martín‐Morales, S Caspani, M Desco… - Advanced …, 2024 - Wiley Online Library
This review offers a comprehensive exploration of optimized drug delivery systems tailored
for controlled release and their crucial role in addressing cerebrovascular diseases …

[HTML][HTML] Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes

S Shahidi, SS Asl, B Gholamigeravand… - Iranian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objective (s): Mesenchymal stem cell (MSC) transplantation represents a promising
approach for treating Alzheimer's disease (AD). These stem cells, however, have a short …