In the nascent mesoderm, TBXT expression must be precisely regulated to ensure that cells
exit the primitive streak and pattern the anterior-posterior axis, but how varying dosage …

Organoids are self-organizing 3D cell culture models that are valuable for studying the
mechanisms underlying both development and disease in multiple species, particularly, in …

Cell autonomous behaviors such as migration and orchestration of cell polarity programs
are required for physiological tissue formation. Micropatterns are cell-adhesive shapes that …

Developmental toxicology is the field of study that examines the effects of chemical and
physical agents on developing organisms. By using principles of systems biology and …

Morphogenesis, the establishment and repair of emergent complex anatomy by groups of
cells, is a fascinating and biomedically-relevant problem. One of its most fascinating aspects …

Abstract Purpose of Review To explore the advances and future research directions in
image analysis and computational modelling of human stem cells (hSCs) for …

I am Dr. Himanshu Kaul, and I am a Royal Academy of Engineering Research Fellow at the
University of Leicester (UK). Currently, I have cross-appointments with the School of …

Precise regulation of both the timing and dosage of gene expression is critical for
thedevelopment of the early embryo and the extraembryonic tissues that support it. These …

Human pluripotent stem cells have opened up unprecedented opportunities to model
human development and disease. Critical to these models is differentiation of stem cells …

The growing number of product variants reduces the utilization of traditional linear assembly
systems and increases the cost of customization for manufacturing companies. Matrix …