A critical review of synthesis procedures, applications and future potential of nanoemulsions

A Naseema, L Kovooru, AK Behera, KPP Kumar… - Advances in Colloid and …, 2021 - Elsevier
Applications of nanotechnology in various spheres have increased manifold as it offers
solution to unsolved problems with higher effectiveness. Nanoemulsions are one such …

Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Progress in brain targeting drug delivery system by nasal route

AR Khan, M Liu, MW Khan, G Zhai - Journal of Controlled Release, 2017 - Elsevier
The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Nanoemulsions for “nose-to-brain” drug delivery

MC Bonferoni, S Rossi, G Sandri, F Ferrari, E Gavini… - Pharmaceutics, 2019 - mdpi.com
The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

Lipid based nanocarriers: a translational perspective

DK Mishra, R Shandilya, PK Mishra - … : Nanotechnology, Biology and …, 2018 - Elsevier
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …

Pharmacokinetics and pharmacodynamics of intranasal solid lipid nanoparticles and nanostructured lipid carriers for nose-to-brain delivery

TTL Nguyen, HJ Maeng - Pharmaceutics, 2022 - mdpi.com
Nose-to-brain drug delivery has been of great interest for the treatment of many central
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …

Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies

PC Pires, AO Santos - Journal of controlled release, 2018 - Elsevier
The treatment of neurodegenerative and psychiatric disorders remains a challenge in
medical research. Several strategies have been developed over the years, either to …

Epilepsy disease and nose-to-brain delivery of polymeric nanoparticles: an overview

T Musumeci, A Bonaccorso, G Puglisi - Pharmaceutics, 2019 - mdpi.com
Epilepsy is the fourth most common global neurological problem, which can be considered a
spectrum disorder because of its various causes, seizure types, its ability to vary in severity …

Novel luteolin-loaded chitosan decorated nanoparticles for brain-targeting delivery in a sporadic Alzheimer's disease mouse model: focus on antioxidant, anti …

H Abbas, NSE Sayed, NAHA Youssef, P ME Gaafar… - Pharmaceutics, 2022 - mdpi.com
Preparation and evaluation of a non-invasive intranasal luteolin delivery for the
management of cognitive dysfunction in Alzheimer's disease (AD) using novel chitosan …

Nano‐delivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives

A Movahedpour, R Taghvaeefar… - CNS Neuroscience …, 2023 - Wiley Online Library
Epilepsy is a common chronic neurological disorder caused by aberrant neuronal electrical
activity. Antiseizure medications (ASMs) are the first line of treatment for people with …