Alzheimer's disease (AD) affects an estimated 44 million individuals worldwide, yet no
therapeutic intervention is available to stop the progression of the dementia …

Although the brain has been considered an insulin-insensitive organ, recent reports on the
location of insulin and its receptors in the brain have introduced new ways of considering …

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer's
disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
accumulation of amyloid plaques and neurofibrillary tangles in the brain. The AD …

Background Herbicides are environmental contaminants that have gained much attention
due to the potential hazards they pose to human health. Glyphosate, the active ingredient in …

Aluminum (Al) is a very common component of the earth's mineral composition. It is not
essential element for life and is a constituent of rather inert minerals. Therefore, it has often …

This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …

Since the original identification of microglia as a principal player in the brain's innate
immune response, microglial activation has been widely studied. Recent studies suggest …

Evidence for the neurotoxicity of extended exposure to low levels of aluminum salts is
described using an animal model treated with aluminum at low levels reflecting those found …

Oxidative stress has been proposed to be an important factor in the pathogenesis of
Alzheimer's disease (AD) and contributed to β-amyloid (A β) generation. Interaction between …