Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Tumour targeting with radiometals for diagnosis and therapy

CF Ramogida, C Orvig - Chemical Communications, 2013 - pubs.rsc.org
Use of radiometals in nuclear oncology is a rapidly growing field and encompasses a broad
spectrum of radiotracers for imaging via PET (positron emission tomography) or SPECT …

Targeted dual-contrast T1-and T2-weighted magnetic resonance imaging of tumors using multifunctional gadolinium-labeled superparamagnetic iron oxide …

H Yang, Y Zhuang, Y Sun, A Dai, X Shi, D Wu, F Li… - Biomaterials, 2011 - Elsevier
Abstract Development of a multifunctional nanoparticle (NP) system allowing for dual-
contrast T 1-and T 2-weighted targeted magnetic resonance (MR) imaging of tumors could …

[HTML][HTML] Roles of focal adhesion proteins in skeleton and diseases

S Chen, T He, Y Zhong, M Chen, Q Yao, D Chen… - … Pharmaceutica Sinica B, 2023 - Elsevier
The skeletal system, which contains bones, joints, tendons, ligaments and other elements,
plays a wide variety of roles in body shaping, support and movement, protection of internal …

Bone development: overview of bone cells and signaling

A Teti - Current osteoporosis reports, 2011 - Springer
Vertebrates evolved elaborating a structure made up of more than 200 bones and cartilages
articulated with one another to form the skeleton, through which locomotion, organ …

Positron emission tomography tracers for imaging angiogenesis

R Haubner, AJ Beer, H Wang, X Chen - European Journal of Nuclear …, 2010 - Springer
Position emission tomography imaging of angiogenesis may provide non-invasive insights
into the corresponding molecular processes and may be applied for individualized treatment …

Bone imaging in prostate cancer: the evolving roles of nuclear medicine and radiology

GJR Cook, G Azad, AR Padhani - Clinical and translational imaging, 2016 - Springer
The bone scan continues to be recommended for both the staging and therapy response
assessment of skeletal metastases from prostate cancer. However, it is widely recognised …

A targeted and pH-responsive bortezomib nanomedicine in the treatment of metastatic bone tumors

M Wang, X Cai, J Yang, C Wang, L Tong… - … applied materials & …, 2018 - ACS Publications
Bortezomib is a boronate proteasome inhibitor widely used as an efficient anticancer drug;
however, the clinical use of bortezomib is hampered by its adverse effects such as …

High tumor uptake of 64Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers

JT Jørgensen, M Persson, J Madsen, A Kjær - Nuclear medicine and …, 2013 - Elsevier
INTRODUCTION: The use of copper-based positron emission tomography (PET) tracers in
cancer studies is increasing. However, as copper has previously been found in high …

Measurement of the rate of copper (II) exchange for 64Cu complexes of bifunctional chelators

V Maheshwari, JLJ Dearling, ST Treves… - Inorganica Chimica …, 2012 - Elsevier
Measurement of the rate of loss of 64Cu from the chelators used in the preparation of 64Cu-
labeled proteins is critical to the development of effective 64Cu-labeled …