Choking agents and chlorine gas–history, pathophysiology, clinical effects and treatment

T Zellner, F Eyer - Toxicology letters, 2020 - Elsevier
Introduction Choking agent exposure, among them chlorine gas, occurs in household or
industrial accidents, chemical warfare and terrorist attacks. Aims Review of published animal …

Inhaled lipid nanocarriers for pulmonary delivery of glucocorticoids: Previous strategies, recent advances and key factors description

MJ Altube, N Perez, EL Romero, MJ Morilla… - International Journal of …, 2023 - Elsevier
In view of the strong anti-inflammatory activity of glucocorticoids (GC) they are used in the
treatment of almost all inflammatory lung diseases. In particular, inhaled GC (IGC) allow high …

Antipyretic effect of inhaled Tetrastigma hemsleyanum polysaccharide on substance and energy metabolism in yeast-induced pyrexia mice via TLR4/NF-κb signaling …

S Fu, X Bao, Z Wang, Y Tang, Q Wu, B Zhu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Tetrastigma hemsleyanum Diels et Gilg, is one of
the perennial evergreen plants with grass vine, which has obvious curative effect on severe …

Self-assembly based aerosolized hyaluronic acid (HA) loaded niosomes for lung delivery: An in-vitro and in-vivo evaluation

P Kulkarni, D Rawtani, S Rajpurohit, S Vasvani… - Journal of Drug Delivery …, 2022 - Elsevier
Hyaluronic acid, a biological macromolecule, was utilized as a drug for loading into
niosomes. The ethanol injection method was used to formulate the niosomes using …

Emergency management of chlorine gas exposure–a systematic review

A Huynh Tuong, T Despréaux, T Loeb… - Clinical …, 2019 - Taylor & Francis
Introduction: Chlorine exposure can lead to pulmonary obstruction, reactive airway
dysfunction syndrome, acute respiratory distress syndrome and, rarely, death. Objective: We …

Discovery of a new long COVID mouse model via systemic histopathological comparison of SARS-CoV-2 intranasal and inhalation infection

D Jeon, SH Kim, J Kim, H Jeong, C Uhm, H Oh… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Intranasal infection is commonly used to establish a SARS-CoV-2 mouse model due to its
non-invasive procedures and a minimal effect from the operation itself. However, mice …

Low-dose intrapulmonary drug delivery device for studies on next-generation therapeutics in mice

AMG Martins, DB Snider, KD Popowski… - … Clinics and Research, 2023 - journals.lww.com
Although nebulizers have been developed for delivery of small molecules in human
patients, no tunable device has been purpose-built for targeted delivery of modern large …

Macrophage-Targeted Nanomedicines

EL Romero, MJ Altube, AP Perez, MJ Morilla - Biotechnology Applied to …, 2023 - Springer
Macrophages are versatile cells of the innate immune system responsible for the control and
progressions of a variety of autoimmune inflammatory, infectious, and metabolic diseases …