Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Metal complex strategies for photo-uncaging the small molecule bioregulators nitric oxide and carbon monoxide

PC Ford - Coordination Chemistry Reviews, 2018 - Elsevier
Photochemical release (uncaging) of small molecule bioregulators (SMBs) such as nitric
oxide (NO) or carbon monoxide (CO) at physiological sites offers exquisite control of timing …

Carbon disulfide. Just toxic or also bioregulatory and/or therapeutic?

AW DeMartino, DF Zigler, JM Fukuto… - Chemical Society …, 2017 - pubs.rsc.org
The overview presented here has the goal of examining whether carbon disulfide (CS2) may
play a role as an endogenously generated bioregulator and/or has therapeutic value. The …

Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control

MA Evans, PJ Huang, Y Iwamoto, KN Ibsen… - Chemical …, 2018 - pubs.rsc.org
Nitric oxide (NO) holds great promise as a treatment for cancer hypoxia, if its concentration
and localization can be precisely controlled. Here, we report a “Trojan Horse” strategy to …

Nitric oxide and cancer: When to give and when to take away?

KM Miranda, LA Ridnour, CL McGinity… - Inorganic …, 2021 - ACS Publications
The mechanistic roles of nitric oxide (NO) during cancer progression have been important
considerations since its discovery as an endogenously generated free radical. Nonetheless …

Cyclometalated gold (III)‐hydride complexes exhibit visible light‐induced thiol reactivity and act as potent photo‐activated anti‐cancer agents

H Luo, B Cao, ASC Chan, RWY Sun… - Angewandte …, 2020 - Wiley Online Library
The specific gold‐sulfur binding interaction renders gold complexes as promising anti‐
cancer agents that can potentially overcome cisplatin resistance; while their unbiased …

Near-infrared and visible photoactivation to uncage carbon monoxide from an aqueous-soluble photoCORM

Q Jiang, Y Xia, J Barrett, A Mikhailovsky, G Wu… - Inorganic …, 2019 - ACS Publications
Multiphoton excitation allows one to access high energy excited states and perform valuable
tasks in biological systems using tissue penetrating near-infrared (NIR) light. Here, we …

Recent advances on the development of NO-releasing molecules (NORMs) for biomedical applications

R Bhowmik, M Roy - European Journal of Medicinal Chemistry, 2024 - Elsevier
Nitric oxide (NO) is an important biological messenger as well as a signaling molecule that
participates in a broad range of physiological events and therapeutic applications in …

From curiosity to applications. A personal perspective on inorganic photochemistry

PC Ford - Chemical Science, 2016 - pubs.rsc.org
Over the past several decades, the photochemistry and photophysics of transition metal
compounds has blossomed from a relatively niche topic to a major research theme …

[HTML][HTML] Direct and indirect approaches to red-shift photoactivated nitric oxide release

HM Elbeheiry, M Schulz - Coordination Chemistry Reviews, 2024 - Elsevier
Nitric oxide (NO) is an important biochemical molecule that is endogenously produced to act
for instance as neurotransmitter, effect cell growth, or to regulate the immune response …