Endocrine dysregulation in COVID-19: molecular mechanisms and insights

C Iosef, AM Matusa, VKM Han… - Frontiers in Endocrinology, 2024 - frontiersin.org
This review describes the impact of COVID-19 on the endocrine system, focusing on cortisol
signaling and growth factor-induced endocrine resistance. As expected, SARS-CoV-2 …

Endocrine aspects of ICU-hospitalized COVID-19 patients

A Diamantopoulos, I Dimopoulou, P Mourelatos… - Journal of Personalized …, 2022 - mdpi.com
The unprecedented scale of the current SARS-CoV-2/COVID-19 pandemic has led to an
extensive—yet fragmented—assessment of its endocrine repercussions; in many reports …

Longitudinal serum proteome characterization of COVID-19 patients with different severities revealed potential therapeutic strategies

S Wu, Y Xu, J Zhang, X Ran, X Jia, J Wang… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 pandemic caused by SARS-CoV-2 is exerting huge pressure on global
healthcare. Understanding of the molecular pathophysiological alterations in COVID-19 …

Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity

AA Mohamed, AA Nour, NM Mosbah, ASM Wahba… - Virology Journal, 2023 - Springer
Abstract Background Coronavirus Disease 2019 (COVID-19) is a worldwide pandemic
challenge spreading enormously within a few months. COVID-19 is characterized by the …

The Importance of Platelet‐Derived Growth Factors as Markers of Survival and Severity of COVID‐19 in Patients Undergoing Monthly Follow‐Up

E Cecerska-Heryć, D Nieszpór, N Serwin… - Mediators of …, 2024 - Wiley Online Library
Platelets are the first to reach the site of tissue damage and secrete substances like platelet
growth factors (GFs), which perform many different functions in the human body. Many …

Obesity-Associated Hepatic Steatosis, Somatotropic Axis Impairment, and Ferritin Levels Are Strong Predictors of COVID-19 Severity

D Masi, E Gangitano, A Criniti, L Ballesio, A Anzuini… - Viruses, 2023 - mdpi.com
The full spectrum of SARS-CoV-2-infected patients has not yet been defined. This study
aimed to evaluate which parameters derived from CT, inflammatory, and hormonal markers …

Serum Insulin-like Growth Factor-Binding Protein-2 as a Prognostic Factor for COVID-19 Severity

P Mester, U Räth, S Schmid, P Amend, D Keller… - Biomedicines, 2024 - mdpi.com
Insulin-like growth factor-binding protein (IGFBP)-2 is a regulator of anabolic pathways,
which become inactivated in severe illness. Here, we measured the serum IGFBP-2 levels of …

Effect of high-calorie formula on weight, height increment, IGF-1 and TLC in growth faltering children: A quasi-experimental study

NA Widjaja, A Hamida, MT Purnomo, A Satjadibrata… - Heliyon, 2024 - cell.com
High-calorie formulas have been used to promote catch-up growth in undernourished
children. The level of insulin-like growth factor 1 (IGF-1) is closely related to weight and …

Circulating Inflammatory Factor Levels in the Early Phase of COVID-19 are Associated with the Progression of Respiratory Failure: A Single-Center Retrospective …

X Xiang, Z Zhang, Y Liu, W Xu, J Gong… - Journal of …, 2023 - Taylor & Francis
Purpose To evaluate the potential relationships between serum interleukin (IL)-2, IL-4, IL-6,
IL-10, IL-17, interferon (IFN)-γ, and tumor necrosis factor (TNF)-α levels and occurrence of …

β-D-mannuronic acid (M2000) and inflammatory cytokines in COVID-19; an in vitro study

B Robat-Jazi, K Ghorban, M Gholami… - Iranian Journal of …, 2022 - ijaai.tums.ac.ir
Abstract coronavirus disease of 2019 (COVID-19) can be complicated by acute respiratory
distress syndrome (ARDS) and may be associated with cytokine storm and multiorgan …