Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example

AP Aleksandrov, I Mirkov, D Tucovic, J Kulas… - Immunology …, 2021 - Elsevier
Cadmium (Cd) represents a unique hazard because of the long biological half-life in
humans (20–30 years). This metal accumulates in organs causing a continuum of …

AMPK/PPAR-γ/NF-κB axis participates in ROS-mediated apoptosis and autophagy caused by cadmium in pig liver

H Wang, A Wang, X Wang, X Zeng, H Xing - Environmental Pollution, 2022 - Elsevier
The experiment was conducted to investigate the effects of Cadmium (Cd) on growth
performance, blood biochemical parameters, oxidative stress, hepatocyte apoptosis and …

Cadmium induces ferroptosis mediated inflammation by activating Gpx4/Ager/p65 axis in pancreatic β-cells

H Hong, X Lin, Y Xu, T Tong, J Zhang, H He… - Science of the Total …, 2022 - Elsevier
Cadmium (Cd) is a widely distributed endocrine disruptor and has been reported to be
closely correlated to the pathogenesis of diabetes. Since pancreatic β-cells loss and …

[HTML][HTML] Genetic and epigenetic modulations in toxicity: The two-sided roles of heavy metals and polycyclic aromatic hydrocarbons from the environment

PI Adegbola, A Adetutu - Toxicology Reports, 2024 - Elsevier
This study emphasizes the importance of considering the metabolic and toxicity mechanisms
of environmental concern chemicals in real-life exposure scenarios. Furthermore …

Response pathways of superoxide dismutase and catalase under the regulation of triclocarban-triggered oxidative stress in Eisenia foetida: Comprehensive …

Z Cui, F He, X Li, Y Li, C Huo, H Wang, Y Qi… - Science of The Total …, 2023 - Elsevier
Triclocarban (TCC) is an emerging environmental contaminant, posing potential ecological
risks. Displaying a high accumulation effect and 120-day half-life in the soil environment, the …

In vivo assessment of molybdenum and cadmium co-induce nephrotoxicity via NLRP3/Caspase-1-mediated pyroptosis in ducks

C Zhang, X Wang, G Nie, Z Wei, S Pi, C Wang… - Journal of Inorganic …, 2021 - Elsevier
Excessive molybdenum (Mo) and cadmium (Cd) cause toxic effects on animals, but their
joint effects on pyroptosis in kidney of ducks remain unclear. 160 healthy 7-day-old ducks …

[HTML][HTML] In vitro degradation behavior and biocompatibility of bioresorbable molybdenum

C Redlich, A Schauer, J Scheibler, G Poehle, P Barthel… - Metals, 2021 - mdpi.com
The degradation behavior and biocompatibility of pure molybdenum (Mo) were investigated.
Dissolution of powder metallurgically manufactured and commercially available Mo was …

[HTML][HTML] Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment

CM Schaupp, D Botta, CC White, DK Scoville… - Redox Biology, 2022 - Elsevier
Antioxidant signaling/communication is among the most important cellular defense and
survival pathways, and the importance of redox signaling and homeostasis in aging has …

Potential of oligonucleotide-and protein/peptide-based therapeutics in the management of toxicant/stressor-induced diseases

I Sadeghian, M Akbarpour, FMA Chafjiri… - Naunyn-Schmiedeberg's …, 2024 - Springer
Exposure to toxicants/stressors has been linked to the development of many human
diseases. They could affect various cellular components, such as DNA, proteins, lipids, and …

Lead (Pb) exposure is associated with changes in the expression levels of circulating miRNAS (miR-155, miR-126) in Mexican women

ÁC Ochoa-Martínez, JA Varela-Silva… - Environmental …, 2021 - Elsevier
The environmental contamination with lead (Pb) is considered a critical issue worldwide.
Therefore, this study aimed to evaluate the expression levels of circulating miRNAs (miR …