Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …

Mast cells are immune cells of the myeloid lineage and are present in connective tissues
throughout the body. The activation and degranulation of mast cells significantly modulates …

Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the
pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to …

Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …

Dendritic cells, macrophages and B cells are regarded as the classical antigen-presenting
cells of the immune system. However, in recent years, there has been a rapid increase in the …