Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study

MA Irvine, D Oller, J Boggis, B Bishop… - The Lancet Public …, 2022 - thelancet.com
Background The US overdose crisis is driven by fentanyl, heroin, and prescription opioids.
One evidence-based policy response has been to broaden naloxone distribution, but how …

Data needs and models for the opioid epidemic

C Blanco, MM Wall, M Olfson - Molecular psychiatry, 2022 - nature.com
The evolving nature of the opioid epidemic and continued increases in overdose deaths
highlight a need for fundamental change in the collection and use of surveillance data to link …

Modeling the evolution of the US opioid crisis for national policy development

TY Lim, EJ Stringfellow, CA Stafford… - Proceedings of the …, 2022 - National Acad Sciences
The opioid crisis is a major public health challenge in the United States, killing about 70,000
people in 2020 alone. Long delays and feedbacks between policy actions and their effects …

Reducing opioid use disorder and overdose deaths in the United States: a dynamic modeling analysis

EJ Stringfellow, TY Lim, K Humphreys… - Science …, 2022 - science.org
Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts …

Estimated costs and outcomes associated with use and nonuse of medications for opioid use disorder during incarceration and at release in Massachusetts

A Chatterjee, M Weitz, A Savinkina… - JAMA Network …, 2023 - jamanetwork.com
Importance Most prisons and jails in the US discontinue medications for opioid use disorder
(MOUD) upon incarceration and do not initiate MOUD prior to release. Objective To model …

Economic evaluation of extended-release buprenorphine for persons with opioid use disorder

JM Flam-Ross, E Marsh, M Weitz… - JAMA Network …, 2023 - jamanetwork.com
Importance In 2017, the US Food and Drug Administration (FDA) approved a monthly
injectable form of buprenorphine, extended-release buprenorphine; published data show …

[HTML][HTML] Trends in out-of-pocket costs for naloxone by drug brand and payer in the US, 2010-2018

ED Peet, D Powell, RL Pacula - JAMA Health Forum, 2022 - jamanetwork.com
Importance Improving access to naloxone is a critical component of the nation's strategy to
curb fatal overdoses in the opioid crisis. Standing or protocol orders, prescriptive authority …

Characterizing initiation, use, and discontinuation of extended-release buprenorphine in a nationally representative United States commercially insured cohort

JR Morgan, AY Walley, SM Murphy, A Chatterjee… - Drug and alcohol …, 2021 - Elsevier
Abstract Background and Aims While the United States is in the midst of an overdose
epidemic, effective treatments are underutilized and commonly discontinued. Innovations in …

Health and economic outcomes of offering buprenorphine in homeless shelters in Massachusetts

A Chatterjee, EA Stewart, SA Assoumou… - JAMA Network …, 2024 - jamanetwork.com
Importance Overdose is the leading cause of death among people experiencing
homelessness (PEH), but engagement in medication treatment is low in this population …

Community selected strategies to reduce opioid-related overdose deaths in the HEALing (helping to end addiction long-term SM) communities study

R Chandler, EV Nunes, S Tan, PR Freeman… - Drug and alcohol …, 2023 - Elsevier
Abstract The Helping End Addictions Long Term (HEALing) Communities Study (HCS)
seeks to significantly reduce overdose deaths in 67 highly impacted communities in …