Millions of workers around the world are exposed to high temperatures, intense physical
activity, and lax labor practices that do not allow for sufficient rehydration breaks. The extent …

Results We identified 1607 articles, of which 26 met inclusion criteria. Eighteen (69%) were
conducted in known CKDu–endemic countries: Sri Lanka (38%), Nicaragua (19%), and El …

Diabetes and hypertension are the predominant risk factors for chronic kidney disease
(CKD) globally. Infectious diseases resulting in glomerulonephritis are also important in low …

Introduction: In the last two decades, chronic kidney disease of unknown etiology (CKDu)
has emerged as a significant contributor to the burden of chronic kidney disease (CKD) in …

There have been several global epidemics of chronic kidney disease of unknown etiology
(CKDu). Some, such as Itai-Itai disease in Japan and Balkan endemic nephropathy, have …

Abstract Background Chronic Kidney Disease (CKD) of uncertain origin (CKDu) has affected
North Central Province (Anuradhapura and Polonnaruwa districts) of Sri Lanka. The cause …

The pollution of water and food through human waste and anthropogenic activities,
including industrial waste and agricultural runoff, is a mounting problem worldwide. Water …

How local groundwater induces chronic kidney disease of unknown etiology (CKDu) in Sri
Lanka is still elusive. This study aims to elucidate the impacts of Sri Lanka's local …

In order to change the current state of chronic kidney disease knowledge and therapeutics, a
fundamental improvement in the understanding of genetic and environmental causes of …

Chronic kidney disease of unknown etiology (CKDu) is a global epidemic. Sri Lanka has
experienced a doubling of the disease every 4 or 5 years since it was first identified in the …