LncRNAs in ovarian cancer progression, metastasis, and main pathways: ceRNA and alternative mechanisms

EA Braga, MV Fridman, AA Moscovtsev… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …

The Role of Phytonutrient Kaempferol in the Prevention of Gastrointestinal Cancers: Recent Trends and Future Perspectives

T Singh, D Sharma, R Sharma, HS Tuli, S Haque… - Cancers, 2024 - mdpi.com
Simple Summary Kaempferol (3, 5, 7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one), a
flavonoid, is richly found in fruits and vegetables. Kaempferol has been proven to reduce …

CDK1 and HSP90AA1 appear as the novel regulatory genes in non-small cell lung cancer: a bioinformatics approach

N Bhattacharyya, S Gupta, S Sharma, A Soni… - Journal of Personalized …, 2022 - mdpi.com
Lung cancer is one of the most invasive cancers affecting over a million of the population.
Non-small cell lung cancer (NSCLC) constitutes up to 85% of all lung cancer cases, and …

[HTML][HTML] Identification of key proteins in host–pathogen interactions between Mycobacterium tuberculosis and Homo sapiens: A systematic network theoretical …

RN Verma, MZ Malik, GP Singh, N Subbarao - Healthcare Analytics, 2022 - Elsevier
Tuberculosis (TB) is an infectious disease caused primarily by the bacterial pathogen
Mycobacterium tuberculosis (Mtb) in humans. The emergence of various drug-resistant Mtb …

[HTML][HTML] A computational biology approach to identify potential protein biomarkers and drug targets for sporadic amyotrophic lateral sclerosis

R Kumar, MZ Malik, TA Thanaraj, SA Bagabir… - Cellular …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the loss of
upper and lower motor neurons. The sporadic ALS (sALS) is a multigenic disorder and the …

[HTML][HTML] Kinless hubs are potential target genes in prostate cancer network

IR Mangangcha, MZ Malik, O Kucuk, S Ali, RKB Singh - Genomics, 2020 - Elsevier
Complex disease networks can be studied successfully using network theoretical approach
which helps in finding key disease genes and associated disease modules. We studied …

Network medicine in ovarian cancer: topological properties to drug discovery

K Chirom, MZ Malik, IR Mangangcha… - Briefings in …, 2022 - academic.oup.com
Network medicine provides network theoretical tools, methods and properties to study
underlying laws governing human interactome to identify disease states and disease …

Identification of microRNA and gene interactions through bioinformatic integrative analysis for revealing candidate signatures in prostate cancer

MM Khan, M Serajuddin, MZ Malik - Gene Reports, 2022 - Elsevier
Abstract Background Prostate cancer (PCa) is a most common diagnosed cancer among
males globally. Despite the decreased PCa mortality, increased prevalence of it creates …

Systematic analysis to identify novel disease indications and plausible potential chemical leads of glutamate ionotropic receptor NMDA type subunit 1, GRIN1

T Bhardwaj, I Ahmad… - Journal of Molecular …, 2023 - Wiley Online Library
Schizophrenia is a mental illness affecting the normal lifestyle of adults and early
adolescents incurring major symptoms as jumbled speech, involvement in everyday …

ACE2 homo-dimerization, human genomic variants and interaction of host proteins explain high population specific differences in outcomes of COVID19

S Sharma, I Singh, S Haider, MZ Malik, K Ponnusamy… - BioRxiv, 2020 - biorxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive single
stranded RNA virus that causes a highly contagious Corona Virus Disease (COVID19). Entry …