Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Harmful fungi in nature not only cause diseases in plants, but also fungal infection and
poisoning when people and animals eat food derived from crops contaminated with them …

Objectives Although the most accepted mechanisms of action of amphotericin B and azoles
are related to ergosterol, it is possible that these drugs have other effects on the fungal cell …

Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause
cryptococcosis, which is usually treated with amphotericin B and fluconazole. However …

This work describes the design, synthesis and antifungal activity of new imidazoles and 1, 2,
4-triazoles derived from eugenol and dihydroeugenol. These new compounds were fully …

Candidiasis caused by Candida albicans is one of the most common microbial infections.
Azoles, polyenes, allylamines, and echinocandins are classes of antifungals used for …

Background and Purpose: The frequency of opportunistic fungal infections in
immunocompromised patients, especially by Candida species, has sharply increased in the …

Cryptococcosis is a fungal infection that is becoming increasingly prevalent worldwide,
particularly among individuals with compromised immune systems, such as HIV patients …

This study demonstrates the excellent in vitro antifungal activity profile of imidazolium ionic
liquids (ILs) against species of opportunistic human mycoses. Several ILs were identified as …

Cryptococcosis caused by Cryptococcus gattii leads to pneumonia and
meningoencephalitis, and has a high mortality rate worldwide due to the inadequacy of …