The COVID-19 pandemic is a serious threat to global health and the global economy. The
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …

Dendritic cells (DCs) are crucial for the appropriate initiation of adaptive immune responses.
During inflammation, DCs capture antigens, mature, and migrate to lymphoid tissues to …

The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral
environments remain mostly undefined. We show that differentiation of CD11blo migratory …

Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

As microneedle-based vaccines possess advantages of high compliance, moderate
invasiveness and convenience that are highly relevant to their unique design, they are …

Antigen transfer refers to the process of intercellular information exchange, where antigenic
components including nucleic acids, antigen proteins/peptides and peptide-major …

The incidence of skin cancer (SC) has dramatically risen over the last decades.
Conventional therapeutic trials possess numerous drawbacks; hence, developing effective …

The balance of type 1 and type 2 immune responses plays a crucial role in anti-helminth
immunity and can either support chronic infection or drive type 2 mediated expulsion of the …

Antigen‐presenting cells (APCs) are critical cells bridging innate and adaptive immune
responses by taking up, processing, and presenting antigens to naïve T cells. At steady …

Immune responses must be rapid, tightly orchestrated, and tailored to the encountered
stimulus. Lymphatic vessels facilitate this process by continuously collecting immunological …