Microfluidic trends in drug screening and drug delivery

J Feng, J Neuzil, A Manz, C Iliescu, P Neuzil - TrAC Trends in Analytical …, 2023 - Elsevier
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …

From organ-on-a-chip to human-on-a-chip: A review of research progress and latest applications

Y Huang, T Liu, Q Huang, Y Wang - ACS sensors, 2024 - ACS Publications
Organ-on-a-Chip (OOC) technology, which emulates the physiological environment and
functionality of human organs on a microfluidic chip, is undergoing significant technological …

The Material World of 3D‐Bioprinted and Microfluidic‐Chip Models of Human Liver Fibrosis

AM Carvalho, R Bansal, CC Barrias… - Advanced …, 2024 - Wiley Online Library
Biomaterials are extensively used to mimic cell–matrix interactions, which are essential for
cell growth, function, and differentiation. This is particularly relevant when developing in vitro …

Needle scattered light guided chiplets-interfaced with AI for advanced biomedical application

BA Taha, EM Abbas, AC Kadhim, AS Azzahrani… - Microelectronic …, 2024 - Elsevier
Recently, integrating artificial intelligence (AI) with needle scattered light (NSL)-guided
chiplets (minuscule circuits) is emerging as a fascinating platform for advanced biomedical …

Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility

D Pamies, J Ekert, MG Zurich, O Frey, S Werner… - Stem Cell Reports, 2024 - cell.com
Cell culture technology has evolved, moving from single-cell and monolayer methods to 3D
models like reaggregates, spheroids, and organoids, improved with bioengineering like …

A generic pump‐free organ‐on‐a‐chip platform for assessment of intestinal drug absorption

Y Guo, Y Xie, J Qin - Biotechnology Journal, 2024 - Wiley Online Library
Organ‐on‐a‐chip technology has shown great potential in disease modeling and drug
evaluation. However, traditional organ‐on‐a‐chip devices are mostly pump‐dependent with …

Advances in Nanomedicine and Biomaterials for Endometrial Regeneration: A Comprehensive Review

Y Liu, D Jia, L Li, M Wang - International Journal of Nanomedicine, 2024 - Taylor & Francis
The endometrium is an extremely important component of the uterus and is crucial for
individual health and human reproduction. However, traditional methods still struggle to …

Tesla valve microfluidics: The rise of forgotten technology

A Purwidyantri, BA Prabowo - Chemosensors, 2023 - mdpi.com
The Tesla valve (TV), a valvular conduit invented by Nicola Tesla over a century ago, has
recently acquired significant attention and application in various fields because of the …

Roadblocks confronting widespread dissemination and deployment of Organs on Chips

CG Alver, E Drabbe, M Ishahak, A Agarwal - Nature Communications, 2024 - nature.com
Organ on Chip platforms hold significant promise as alternatives to animal models or
traditional cell cultures, both of which poorly recapitulate human pathophysiology and …

Review on new approach methods to gain insight into the feto-maternal interface physiology

R Menon, LJ Muglia, LH Levin - Frontiers in Medicine, 2023 - frontiersin.org
Non-human animals represent a large and important feature in the history of biomedical
research. The validity of their use, in terms of reproducible outcomes and translational …