Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

The isolation and identification of the discrete plant cannabinoids in marijuana revived
interest in analyzing historical therapeutic claims made for cannabis in clinical case studies …

The CB1 cannabinoid receptor is a G-protein coupled receptor highly expressed throughout
the central nervous system that is a promising target for the treatment of various disorders …

Cannabis has been used to treat convulsions and other disorders since ancient times. In the
last few decades, preclinical animal studies and clinical investigations have established the …

Phytocannabinoids isolated from the cannabis plant have broad potential in medicine that
has been well recognized for many centuries. It is presumed that these lipid soluble …

Cannabis use induces a plethora of actions on the CNS via its active chemical ingredients,
the so-called phytocannabinoids. These compounds have been frequently associated with …

Studies have demonstrated the neuroprotective effect of cannabidiol (CBD) and other
Cannabis sativa L. derivatives on diseases of the central nervous system caused by their …

The Aβ (25–35) fraction mimics the toxic effects of the complete peptide Aβ (1–42) because
this decapeptide is able to cause memory impairment and neurodegenerative events …

Cannabinoid and PPAR receptors show well established interactions in a set of
physiological effects. Regarding the seizure-modulating properties of both classes of …