Cell death was once believed to be the result of one of two distinct processes, apoptosis
(also known as programmed cell death) or necrosis (uncontrolled cell death); in recent …

Caspases are proteolytic enzymes that belong to the cysteine protease family and play a
crucial role in homeostasis and programmed cell death. Caspases have been broadly …

Inflammation is increasingly recognized as being a critical contributor to both normal
development and injury outcome in the immature brain. The focus of this Review is to …

Caspases are a family of endoproteases that provide critical links in cell regulatory networks
controlling inflammation and cell death. The activation of these enzymes is tightly controlled …

A wide variety of pathogenic microorganisms have been demonstrated to cause eukaryotic
cell death, either as a consequence of infecting host cells or by producing toxic products …

Pro-inflammatory programmed cell death: Trends in Microbiology Skip to Main Content
Advertisement Trends in Microbiology This journal offers authors two options (open access or …

Neuronal apoptosis sculpts the developing brain and has a potentially important role in
neurodegenerative diseases. The principal molecular components of the apoptosis …

Inflammation is increasingly recognized as being of both physiological and pathological
importance in the immature brain. The rationale of this review is to present an update on this …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Inflammation is an innate immune response to infection or tissue damage that is designed to
limit harm to the host, but contributes significantly to ischemic brain injury following stroke …