The Rubinstein-Taybi syndrome (RSTS) is a rare congenital developmental disorder
characterized by a typical facial dysmorphism, distal limb abnormalities, intellectual …

The OMICs cascade describes the hierarchical flow of information through biological
systems. The epigenome sits at the apex of the cascade, thereby regulating the RNA and …

Autism spectrum disorders (ASD) comprise a range of neurodevelopmental pathologies
characterized by deficits in social interaction and repetitive behaviors, collectively affecting …

Chromatin structure is an essential regulator of gene expression. Its state of compaction
contributes to the regulation of genetic programs, in particular during differentiation …

Patients carrying autosomal dominant mutations in the histone/lysine acetyl transferases
CBP or EP300 develop a neurodevelopmental disorder: Rubinstein-Taybi syndrome …

ABSTRACT Genetic variants affecting Heterogeneous Nuclear Ribonucleoprotein U
(HNRNPU) have been identified in several neurodevelopmental disorders (NDDs) …

Simple Summary Cancer is initiated by alterations in specific genes. However, at late stages,
cancer cells become metastatic not necessarily through continuous accumulation of …

Rubinstein-Taybi syndrome (RTS) is a rare and severe genetic developmental disorder
characterized by multiple congenital anomalies and intellectual disability. CREBBP and …

Rubinstein-Taybi syndrome (RSTS) is a rare neurodevelopmental disorder caused by
mutations in CREBBP or EP300 genes encoding CBP/p300 lysine acetyltransferases. We …

Taking advantage of the fast-growing knowledge of RNA-binding proteins (RBPs) we review
the signature of downregulated genes for RBPs in the transcriptome of induced pluripotent …