Compounds featuring aziridine moieties are widely known and extensively reported in the
literature. Due to their great potential from both synthetic and pharmacological points of …

Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

We created new thiosemicarbazones and their cyclized heterocyclic compounds, examined
them, and evaluated their biological activity in silico and in vitro. Two pyrene-based …

Breast cancer (BC) is one of the most prevalent malignancies and the major contributor to
cancer mortality in women globally, with a high degree of heterogeneity and a dismal …

This review meticulously examines the synthesis techniques for 1, 3, 4-thiadiazole
derivatives, focusing on cyclization, condensation reactions and functional group …

With a lack of targeted therapy and significantly high metastasis, heterogeneity, and relapse
rates, Triple‐Negative Breast Cancer (TNBC) offers substantial treatment challenges and …

Herein, we present an overview of continuous flow chemistry, including photoflow and
electroflow technologies in the preparation of active pharmaceutical ingredients (APIs) and …

The vascular endothelial growth factor receptor (VEGFR) system is the key component for
controlling angiogenesis in cancer cells. Blocking vascular endothelial growth factor …

Cancer stem cells (CSCs) are the cells in a primary tumor that have the opportunity to self-
renew as well as differentiate into certain cell types, thus forming a mixed tumor. CSCs have …

An efficient one-pot three-component reaction for the synthesis of [1, 3] dioxolo [4′, 5′: 6,
7] chromeno [2, 3-b] pyridines 4 (a–i) has been developed. Synthesis was achieved by …