[HTML][HTML] hERG K+ channels: structure, function, and clinical significance
The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …
Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo
M Levin - Molecular biology of the cell, 2014 - Am Soc Cell Biol
In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
Molecular bioelectricity in developmental biology: new tools and recent discoveries: control of cell behavior and pattern formation by transmembrane potential …
M Levin - Bioessays, 2012 - Wiley Online Library
Significant progress in the molecular investigation of endogenous bioelectric signals during
pattern formation in growing tissues has been enabled by recently developed techniques …
pattern formation in growing tissues has been enabled by recently developed techniques …
Regulation of cell behavior and tissue patterning by bioelectrical signals: challenges and opportunities for biomedical engineering
M Levin, CG Stevenson - Annual review of biomedical …, 2012 - annualreviews.org
Achieving control over cell behavior and pattern formation requires molecular-level
understanding of regulatory mechanisms. Alongside transcriptional networks and …
understanding of regulatory mechanisms. Alongside transcriptional networks and …
Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation
Alongside the well-known chemical modes of cell-cell communication, we find an important
and powerful system of bioelectrical signaling: changes in the resting voltage potential (V …
and powerful system of bioelectrical signaling: changes in the resting voltage potential (V …
Planarian regeneration as a model of anatomical homeostasis: recent progress in biophysical and computational approaches
Planarian behavior, physiology, and pattern control offer profound lessons for regenerative
medicine, evolutionary biology, morphogenetic engineering, robotics, and unconventional …
medicine, evolutionary biology, morphogenetic engineering, robotics, and unconventional …
[HTML][HTML] Endogenous voltage potentials and the microenvironment: bioelectric signals that reveal, induce and normalize cancer
Cancer may be a disease of geometry: a misregulation of the field of information that
orchestrates individual cells' activities towards normal anatomy. Recent work identified …
orchestrates individual cells' activities towards normal anatomy. Recent work identified …
The electrophysiological development of cardiomyocytes
The generation of human cardiomyocytes (CMs) from human pluripotent stem cells (hPSCs)
has become an important resource for modeling human cardiac disease and for drug …
has become an important resource for modeling human cardiac disease and for drug …
Electrophysiologic substrate in congenital long QT syndrome: noninvasive mapping with electrocardiographic imaging (ECGI)
Background—Congenital Long QT syndrome (LQTS) is an arrhythmogenic disorder that
causes syncope and sudden death. Although its genetic basis has become well-understood …
causes syncope and sudden death. Although its genetic basis has become well-understood …
Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities
M Levin - Wiley Interdisciplinary Reviews: Systems Biology and …, 2013 - Wiley Online Library
Transformative impact in regenerative medicine requires more than the reprogramming of
individual cells: advances in repair strategies for birth defects or injuries, tumor …
individual cells: advances in repair strategies for birth defects or injuries, tumor …