Alzheimer's disease: risk factors and potentially protective measures

MVF Silva, CMG Loures, LCV Alves… - Journal of biomedical …, 2019 - Springer
Alzheimer's disease (AD) is the most common type of dementia and typically manifests
through a progressive loss of episodic memory and cognitive function, subsequently causing …

The bilingual adaptation: How minds accommodate experience.

E Bialystok - Psychological bulletin, 2017 - psycnet.apa.org
According to some estimates, more than half of the world's population is multilingual to some
extent. Because of the centrality of language use to human experience and the deep …

Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria

B Dubois, H Hampel, HH Feldman, P Scheltens… - Alzheimer's & …, 2016 - Elsevier
During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …

[HTML][HTML] Summary of the evidence on modifiable risk factors for cognitive decline and dementia: a population-based perspective

M Baumgart, HM Snyder, MC Carrillo, S Fazio… - Alzheimer's & …, 2015 - Elsevier
An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies

JS Kuiper, M Zuidersma, RCO Voshaar… - Ageing research …, 2015 - Elsevier
It is unclear to what extent poor social relationships are related to the development of
dementia. A comprehensive systematic literature search identified 19 longitudinal cohort …

The association between social engagement, loneliness, and risk of dementia: a systematic review and meta-analysis

R Penninkilampi, AN Casey, MF Singh… - Journal of Alzheimer's …, 2018 - content.iospress.com
It has been reported that social engagement may be associated with dementia risk. We
searched PubMed, EMBASE, PsycINFO, CINAHL, LILACS, Biomed Central, Scopus, and …

Normal cognitive aging

CN Harada, MCN Love… - Clinics in geriatric …, 2013 - geriatric.theclinics.com
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Brain reserve, cognitive reserve, compensation, and maintenance: operationalization, validity, and mechanisms of cognitive resilience

Y Stern, CA Barnes, C Grady, RN Jones, N Raz - Neurobiology of aging, 2019 - Elsevier
Significant individual differences in the trajectories of cognitive aging and in age-related
changes of brain structure and function have been reported in the past half-century. In some …

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Cognitive reserve in ageing and Alzheimer's disease

Y Stern - The Lancet Neurology, 2012 - thelancet.com
The concept of cognitive reserve provides an explanation for differences between
individuals in susceptibility to age-related brain changes or pathology related to Alzheimer's …