Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The incidence of chronic kidney disease (CKD) is increasing worldwide, with more than 26
million people suffering from CKD in the United States alone. More patients with CKD die of …

Aims We explored the relationship between inflammation, renalase an anti-inflammatory
protein, and acute chest pain with coronary microvascular dysfunction (CMD). Methods and …

Background/Aims: Renalase, a novel flavoprotein expressed in the kidney and heart,
reduces renal tubular necrosis and apoptosis, which suggests that it might protect against …

Despite great advances in medicine, the proper treatment of arterial hypertension (AH),
diabetes mellitus (DM) and chronic kidney disease (CKD) remains a major challenge …

African Americans carrying two apolipoprotein L1 gene (APOL1) renal risk variants have a
high risk for nephropathy. However, only a minority develops end-stage renal disease …

Cardiovascular autonomic dysfunction is a major complication of chronic kidney disease
(CKD), likely contributing to the high incidence of cardiovascular mortality in this patient …

Renalase was discovered as a protein synthesized by the kidney and secreted in blood
where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested …

Background Contrast-induced nephropathy (CIN) is the third leading cause of hospital-
acquired acute renal failure. Oxidative stress, apoptosis and inflammation play crucial roles …