Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)

V Ehrlich, W Bil, R Vandebriel, B Granum, M Luijten… - Environmental …, 2023 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) are of public health concern,
because of their ubiquitous and extremely persistent occurrence, and depending on their …

Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

J Lv, Y Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Fluoropolymers have unique physicochemical properties such as hydrophobicity and
lipophobicity, good chemical stability and bio-inertness, low surface energy and phase …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Carcinogenesis: Failure of resolution of inflammation?

A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluorooctane sulfonic acid (PFOS) and …

Serum vaccine antibody concentrations in children exposed to perfluorinated compounds

P Grandjean, EW Andersen, E Budtz-Jørgensen… - Jama, 2012 - jamanetwork.com
Context Perfluorinated compounds (PFCs) have emerged as important food contaminants.
They cause immune suppression in a rodent model at serum concentrations similar to those …

Comparative chronic toxicities of PFOS and its novel alternatives on the immune system associated with intestinal microbiota dysbiosis in adult zebrafish

J Huang, Q Wang, S Liu, H Lai, W Tu - Journal of Hazardous Materials, 2022 - Elsevier
2 Chlorinated polyfluorinated ether sulfonate (F-53B) and sodium p-perfluorous
nonenoxybenzene sulfonate (OBS) are widely used as perfluorooctane sulfonate (PFOS) …

Immunotoxicity of perfluorinated compounds: recent developments

JC DeWitt, MM Peden-Adams, JM Keller… - Toxicologic …, 2012 - journals.sagepub.com
Perfluorinated compounds (PFCs) are environmentally widespread, persistent, and
bioaccumulative chemicals with multiple toxicities reported in experimental models and …

Molecular mechanisms of PFOA-induced toxicity in animals and humans: Implications for health risks

K Li, P Gao, P Xiang, X Zhang, X Cui, LQ Ma - Environment international, 2017 - Elsevier
As an emerging persistent organic pollutant (POP), perfluorooctanoate (PFOA) is one of the
most abundant perfluorinated compounds (PFCs) in the environment. This review …

Application of the key characteristics of carcinogens to per and polyfluoroalkyl substances

AM Temkin, BA Hocevar, DQ Andrews… - International journal of …, 2020 - mdpi.com
Per-and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally
persistent chemicals used in industrial and consumer products. Human exposure to PFAS is …