[HTML][HTML] A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology

H Chen, PK Nwe, Y Yang, CE Rosen, AA Bielecka… - Cell, 2019 - cell.com
The intestinal microbiota produces tens of thousands of metabolites. Here, we used host
sensing of small molecules by G-protein coupled receptors (GPCRs) as a lens to illuminate …

Congenital pouch colon

R Chadha, NA Khan - Journal of Indian Association of Pediatric …, 2017 - journals.lww.com
Congenital pouch colon (CPC) is an unusual abnormality in which a pouch-like dilatation of
a shortened colon is associated with an anorectal malformation. It is categorized into four …

[PDF][PDF] In vitro study of acetylcholine and histamine induced contractions in colon and rectum of adult and neonate rats

S Singh, MB Mandal - Indian J Physiol Pharmacol, 2013 - ijpp.com
Contractile mechanisms of different parts of the gut in adult and neonate may not be
identical due to developmental processes. The present study was undertaken to investigate …

[PDF][PDF] Effects of chronic ingestion of Bisphenol A on gut contractility in rats

D Dixit, SK Singh, AK Tiwari, MB Mandal - National Journal of …, 2017 - njppp.com
ABSTRACT Background: Bisphenol A (BPA) is a plastic toxin widely used in manufacturing
of plastic containers. It is known to produce a variety of toxic effects on body functions …

Histopathological and immunohistochemical findings in congenital pouch colon: A prospective study

H Udawat, V Nunia, P Mathur, HP Udawat, KL Gaur… - Pathobiology, 2017 - karger.com
Background: There is a paucity of literature on the histopathological aspects of congenital
pouch colon (CPC) and immunohistochemical (IHC) assessment has not been reported. So …

Capsaicin fails to produce changes in contractile tension in large gut of neonate rats

S Singh, P Sharma, D Dixit, MB Mandal - Indian Journal of Physiology and …, 2023 - ijpp.com
Objectives: Capsaicin, the most pungent constituent of chilli pepper (Capsicum annuum L.),
is known to alter the physiological activity of the gut. Capsaicin mediates its action through a …

Congenital pouch colon

AK Saxena, P Mathur - Pediatric Surgery: General Principles and Newborn …, 2020 - Springer
Congenital pouch colon (CPC) is a rare form of anorectal malformation, in which the entire
colon is replaced by an enormously dilated pouch that communicates with a fistula to the …

[PDF][PDF] Plastic toxin Bisphenol A depresses the contractile activity of rat ileum and colon in vitro

K Nirja, P Sharma, AK Tiwari, MB Mandal - Indian J Physiol Pharmacol, 2018 - ijpp.com
The chemical, 4, 4'-Isopro-pylidenediphenol, commonly known as Bisphenol A (BPA), is
produced in a high volume and used primarily in the production of polycarbonate plastics …

[PDF][PDF] A comparison of effects of bisphenol A and bisphenol S on rat gut contractility in vitro after acute exposure

P Sharma, MB Mandal - National Journal of Physiology, Pharmacy and …, 2019 - njppp.com
Background: Prevailing standard of living allows generous usage of plastic containers to
store, transport, and serve edibles. A chemical named bisphenol A (BPA) leaches from …

Role of nitric oxide in determination of large intestinal contractility in neonatal rats

S Singh, P Sharma, D Dixit, MB Mandal - Indian Journal of Physiology and …, 2024 - ijpp.com
Objectives: Nitric oxide (NO) plays a key role in inhibiting the contractility of gut smooth
muscles in various species, and NG-nitro-L-arginine methyl ester (L-NAME) is a critical NO …