The double-stranded RNA binding domain (dsRBD) is a small protein domain of 65–70
amino acids adopting an αβββα fold, whose central property is to bind to double-stranded …

Double‐stranded (ds) RNA has diverse roles in gene expression and regulation, host
defense, and genome surveillance in bacterial and eukaryotic cells. A central aspect of …

Proper regulation of ribosome biosynthesis is mandatory for cellular adaptation, growth and
proliferation. Ribosome biogenesis is the most energetically demanding cellular process …

Despite their crucial role in the stabilization of biomolecular structures and their almost
ubiquitous involvement in biomolecular reactions, such as enzymatic cleavage or ligand …

Specific recognition of double-stranded RNA (dsRNA) by dsRNA-binding domains
(dsRBDs) is involved in a large number of biological and regulatory processes. Although …

DNA trinucleotide repeats (TRs) can exhibit dynamic expansions by integer numbers of
trinucleotides that lead to neurodegenerative disorders. Strand slipped hairpins during DNA …

Single‐stranded DNA or double‐stranded DNA has the potential to adopt a wide variety of
unusual duplex and hairpin motifs in the presence (trans) or absence (cis) of ligands …

RNA hairpins are the most commonly occurring secondary structural elements in RNAs and
serve as nucleation sites for RNA folding, RNA–RNA, and RNA–protein interactions. RNA …

The translation of reverse transcriptase and other essential viral proteins from the HIV‐1 Pol
mRNA requires a programmed–1 ribosomal frameshift. This frameshift is induced by two …

Summary dsRBDs often bind dsRNAs with some specificity, yet the basis for this is poorly
understood. Rnt1p, the major RNase III in Saccharomyces cerevisiae, cleaves RNA …