Has the shortage of fludarabine altered the current paradigm of lymphodepletion in favor of bendamustine?
D Filioglou, M Husnain, S Khurana… - Frontiers in …, 2023 - frontiersin.org
The most common lymphodepletion regimen used prior to infusion of chimeric antigen
receptor-T cells (CAR-T) is cyclophosphamide (CY) in combination with fludarabine (Flu)(CY …
receptor-T cells (CAR-T) is cyclophosphamide (CY) in combination with fludarabine (Flu)(CY …
Partially replacing cyclophosphamide with bendamustine in combination with cyclosporine A improves survival and reduces xenogeneic graft-versus-host-disease
KE Gilman, MJ Cracchiolo, AP Matiatos… - Frontiers in …, 2023 - frontiersin.org
Introduction The use of allogeneic hematopoietic cell transplantation (allo-HCT) for treating
hematological disorders is increasing, but the development of graft-versus-host disease …
hematological disorders is increasing, but the development of graft-versus-host disease …
Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
MJ Cracchiolo, L Davis, AP Matiatos, DW Davini… - Cancer Chemotherapy …, 2024 - Springer
Purpose The purpose of this study was to analyze potential differences in antitumor efficacy
and pharmacokinetics between intravenous (IV) bendamustine and a novel orally …
and pharmacokinetics between intravenous (IV) bendamustine and a novel orally …