Endometriosis is a complex, inflammatory disease that affects 6-10% of reproductive-aged
women. Almost half of the women with endometriosis experience infertility. Despite the …

The role of the immune system in the development of senile osteoporosis, which arises
primarily through the effects of estrogen deficiency and secondary hyperparathyroidism, is …

A receptive endometrial environment requires adequate immunological tolerance to protect
the implanting embryo from maternal immune rejection. Studies in mice implicate CD4+ …

Transforming growth factor β1 (TGFβ1), an important pleiotropic, immunoregulatory cytokine,
uses distinct signaling mechanisms in lymphocytes to affect T-cell homeostasis, regulatory T …

Objectives The NLRP3/ASC inflammasome drives host defence and autoinflammatory
disorders by activating caspase-1 to trigger the secretion of mature interleukin (IL)-1β/IL-18 …

Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and
immunosuppressive properties that is upregulated after injury, but also expressed in the …

The two regions of decidua, decidua basalis and decidua parietalis, differ in the extent of
trophoblast invasion and consequently in cytokines and other biological mediators …

Transforming growth factor-β (TGF-β) is a potent regulatory cytokine with diverse effects on
hemopoietic cells. The pivotal function of TGF-β in the immune system is to maintain …

Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and
chronic inflammatory diseases. HTLV-1 bZIP factor (HBZ) is transcribed as an antisense …

Foxp3+ T regulatory cell (Treg) subsets play a crucial role in the maintenance of immune
homeostasis against self-antigen. The lack or dysfunction of these cells is responsible for the …