Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Inside (sight) of tiny communicator: exosome biogenesis, secretion, and uptake

AS Jadli, N Ballasy, P Edalat, VB Patel - Molecular and cellular …, 2020 - Springer
Discovered in the late 1980s as an extracellular vesicle of endosomal origin secreted from
reticulocytes, exosomes recently gained scientific attention due to its role in intercellular …

Extracellular vesicles as a novel mediator of interkingdom communication

J Huang, X Wang, Z Wang, L Deng, Y Wang… - Cytokine & Growth …, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized lipid bilayer-delimited particles secreted from
almost all types of cells including bacteria, mammals and plants, and are presumed to be …

Applications of mesenchymal stem cell-exosome components in wound infection healing: new insights

A Fakouri, ZS Razavi, AT Mohammed… - Burns & …, 2024 - academic.oup.com
The healing process at a wound is made up of many types of cells, growth factors, the
extracellular matrix, nerves and blood vessels all interacting with each other in complex and …

Exosomal RNAs: novel potential biomarkers for diseases—a review

J Wang, BL Yue, YZ Huang, XY Lan, WJ Liu… - International Journal of …, 2022 - mdpi.com
Exosomes are a subset of nano-sized extracellular vesicles originating from endosomes.
Exosomes mediate cell-to-cell communication with their cargos, which includes mRNAs …

Exosome: a new player in translational nanomedicine

H Aheget, M Tristán-Manzano, L Mazini… - Journal of Clinical …, 2020 - mdpi.com
Exosomes are extracellular vesicles released by the vast majority of cell types both in vivo
and ex vivo, upon the fusion of multivesicular bodies (MVBs) with the cellular plasma …

Looking to the Future of the Role of Macrophages and Extracellular Vesicles in Neuroinflammation in ALS

E Carata, M Muci, S Di Giulio, S Mariano… - International journal of …, 2023 - mdpi.com
Neuroinflammation is a common pathological feature of amyotrophic lateral sclerosis (ALS).
Although scientific evidence to date does not allow defining neuroinflammation as an ALS …

Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs

M Chinnappan, A Srivastava, N Amreddy, M Razaq… - Cancer letters, 2020 - Elsevier
Exosomes are small membranous vesicles implicated in intercellular signalling. Through
their uncanny ability to carry and deliver donor cellular cargo (biomolecules) to target cells …

Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

F Malekian, A Shamsian, SP Kodam… - The Journal of …, 2023 - Wiley Online Library
Exosomes are membrane‐bound vesicles that are released by most cells. They carry
nucleic acids, cytokines, growth factors, proteins, lipids, and metabolites. They are …

Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction

E Martínez‐Klimova, OE Aparicio‐Trejo… - …, 2020 - Wiley Online Library
Obstructive nephropathy favors the progression to chronic kidney disease (CKD), a severe
health problem worldwide. The unilateral ureteral obstruction (UUO) model is used to study …