Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …

Background In an ongoing outbreak of haemolytic uraemic syndrome and bloody diarrhoea
caused by a virulent Escherichia coli strain O104: H4 in Germany (with some cases …

Many important interactions between bacterial pathogens and their hosts are highly specific
binding events that involve host or pathogen carbohydrate structures (glycans). Glycan …

Most cases of diarrhoea-associated haemolytic uraemic syndrome (HUS) are caused by
Shiga-toxin-producing bacteria; the pathophysiology differs from that of thrombotic …

The objective of this review is to highlight the importance of cattle in human disease due to
Shiga toxin-producing Escherichia coli (STEC) and to discuss features of STEC that are …

Enterohaemorrhagic Escherichia coli (EHEC) are the pathogenic subgroup of Shiga toxin
(Stx)-producing E. coli. EHEC can cause non-bloody and bloody diarrhoea, and the …

Hemolytic uremic syndrome (HUS) is a disease of nonimmune (Coombs negative) hemolytic
anemia, low platelet count, and renal impairment (1). Anemia is severe and …

Protein folding in the endoplasmic reticulum (ER) is an essential cell function. To safeguard
this process in the face of environmental threats and internal stressors, cells mount an …

In 1982, hemorrhagic colitis and hemolytic-uremic syndrome were linked to infection with
Escherichia coli O157: H7, a serotype now classified as Shiga toxin–producing E. coli …