Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer

S Delaunay, F Rapino, L Tharun, Z Zhou… - Journal of Experimental …, 2016 - rupress.org
Quantitative and qualitative changes in mRNA translation occur in tumor cells and support
cancer progression and metastasis. Posttranscriptional modifications of transfer RNAs …

A three layered histone epigenetics in breast cancer metastasis

D Nandy, SM Rajam, D Dutta - Cell & Bioscience, 2020 - Springer
Thanks to the advancement in science and technology and a significant number of cancer
research programs being carried out throughout the world, the prevention, prognosis and …

Epigenetic regulation of breast cancer metastasis

C Thakur, Y Qiu, A Pawar, F Chen - Cancer and Metastasis Reviews, 2024 - Springer
Breast cancer is the most frequently diagnosed malignancy and the second leading cause of
cancer-related mortality among women worldwide. Recurrent metastasis is associated with …

[HTML][HTML] TFEB-VEGFA (6p21. 1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management

S Gupta, SH Johnson, G Vasmatzis, B Porath… - Modern Pathology, 2017 - Elsevier
A subset of renal cell carcinomas shows TFEB overexpression secondary to MALAT1-TFEB
gene fusion. As alternate mechanisms of TFEB overexpression are likely to have the same …

RETRACTED ARTICLE: MiR-138-5p Inhibits the Proliferation of Gastric Cancer Cells by Targeting DEK

W Zhang, K Liao, D Liu - Cancer Management and Research, 2020 - Taylor & Francis
Zhang W, Liao K, Liu D. Cancer Manag Res. 2020; 12: 8137–8147. The Editor and
Publisher of Cancer Management and Research are retracting the published article …

miR-181-5p attenuates neutrophilic inflammation in asthma by targeting DEK

Y Song, Z Wang, J Jiang, Y Piao, Q Bai, Q Piao… - International …, 2022 - Elsevier
We investigated the regulatory role of miR-181b-5p in neutrophilic asthma and its
mechanisms by targeting DEK. DEK, matrix metalloproteinase (MMP)-2, and MMP-9 were …

[HTML][HTML] Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer

D Lin, X Dong, K Wang, AW Wyatt, F Crea, H Xue… - …, 2014 - pmc.ncbi.nlm.nih.gov
Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer which
does not respond to hormone therapy. Research of NEPC has been hampered by a lack of …

[HTML][HTML] IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival

AK Adams, LC Bolanos, PJ Dexheimer, RA Karns… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The chromatin-binding DEK protein was recently reported to promote the growth of HPV+
and HPV− head and neck squamous cell carcinomas (HNSCCs). Relevant cellular and …

Promotion of cell proliferation by the proto‐oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization

T Nakashima, H Tomita, A Hirata, K Ishida… - Cancer …, 2017 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) develops through a multistep carcinogenic process
involving field cancerization. The DEK gene is a proto‐oncogene with functions in genetic …

Hsa_circ_0001479 accelerates tumorigenesis of gastric cancer and mediates immune escape

J Zang, L Xiao, X Shi, S Liu, Y Wang, B Sun… - International …, 2023 - Elsevier
Gastric cancer (GC) is a common fatal malignant tumor of the digestive tract, particularly in
Asia. Circular RNA (circRNA) has been proved to regulate malignancy progression and …