Progress and prospects of biomarkers in primary liver cancer

YX Gao, TW Yang, JM Yin… - International …, 2020 - spandidos-publications.com
Tumor biomarkers are important in the early screening, diagnosis, therapeutic evaluation,
recurrence and prognosis prediction of tumors. Primary liver cancer is one of the most …

Serum biomarkers for the prediction of hepatocellular carcinoma

JD Debes, PA Romagnoli, J Prieto, M Arrese… - Cancers, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is a leading cause of global cancer death. Major etiologies
of HCC relate to chronic viral infections as well as metabolic conditions. The survival rate of …

miRNAs as potential biomarkers for viral hepatitis B and C

D Loureiro, I Tout, S Narguet, SM Benazzouz… - Viruses, 2020 - mdpi.com
Around 257 million people are living with hepatitis B virus (HBV) chronic infection and 71
million with hepatitis C virus (HCV) chronic infection. Both HBV and HCV infections can lead …

Current status of hepatocellular carcinoma detection: screening strategies and novel biomarkers

WS Ayoub, J Steggerda, JD Yang… - … in medical oncology, 2019 - journals.sagepub.com
Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality
worldwide. Delayed diagnosis is a major factor responsible for the poor prognosis of HCC …

Non-coding RNAs in hepatocellular carcinoma: Insights into regulatory mechanisms, clinical significance, and therapeutic potential

Q Han, M Wang, X Dong, F Wei, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a complex and heterogeneous malignancy with high
incidence and poor prognosis. In addition, owing to the lack of diagnostic and prognostic …

Circulating microRNAs (miR‐16, miR‐22, miR‐122) expression and early diagnosis of hepatocellular carcinoma

Y Fang, D Yan, L Wang, J Zhang… - Journal of clinical …, 2022 - Wiley Online Library
Abstract Purpose Circulating microRNA (miRNA) has been reported to have diagnostic
value in multiple tumors. To identify serum miRNAs for early diagnosis of hepatocellular …

HCC biomarkers–state of the old and outlook to future promising biomarkers and their potential in everyday clinical practice

S Schlosser, D Tümen, B Volz, K Neumeyer… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the most common and deadly tumors worldwide.
Management of HCC depends on reliable biomarkers for screening, diagnosis, and …

The role and mechanism of action of microRNA-122 in cancer: Focusing on the liver

ME Al-Gazally, R Khan, M Imran… - International …, 2023 - Elsevier
Abstract microRNA-122 (miR-122) is a highly conserved microRNA that is predominantly
expressed in the liver and plays a critical role in the regulation of liver metabolism. Recent …

MicroRNA profiling identifies biomarkers in head kidneys of common carp exposed to cadmium

Q Liu, J Yang, Y Gong, J Cai, Y Zheng, Y Zhang, D Yu… - Chemosphere, 2020 - Elsevier
Cadmium (Cd) is an increasingly important environmental pollutant due to its high toxicity to
fish and aquatic animals. In the present study, we cultured common carp (Cyprinus carpio L.) …

Circulating liver-specific microRNAs as noninvasive diagnostic biomarkers of hepatic diseases in human

G Musaddaq, N Shahzad, MA Ashraf, MI Arshad - Biomarkers, 2019 - Taylor & Francis
Context: Hepatitis is an endemic disease worldwide leading to chronic and debilitating
cancers. The viral agents and hepatotoxic substances lead to damage of hepatocytes and …