Because of the difficulties of recognizing allergic bronchopulmonary aspergillosis (ABPA) in
the context of cystic fibrosis (because of overlapping clinical, radiographic, microbiologic …

Allergen immunotherapy (AIT) has been practised since 1911 and remains the only therapy
proven to modify the natural history of allergic diseases. Although efficacious in carefully …

BACKGROUND: Peanut allergy is a life-threatening condition; there is currently no cure.
Although whole allergen extracts are used for specific immunotherapy for many allergies …

Careful selection of dominant T cell epitope peptides of major allergens that display
degeneracy for binding to a wide array of MHC class II molecules allows induction of clinical …

Background Peanut allergy is a life‐threatening condition; there is currently no cure. While
whole allergen extracts are used for specific immunotherapy for many allergies, they can …

Predisposition co develop Various autoimmune disorders has been associated with certain
HLA class II molecules but there is a lack of information on che pathophysiological rule of …

Considerable evidence suggests that IL-10 may have a role in the manifestation of atopic
disease. We sought to test the hypothesis that at the single cell level, allergen-specific T …

Allergen-specific T cells play an important role in the pathophysiology of atopic allergies.
Recently, cDNAs that encode many important allergens have been cloned and their amino …

Background Genes linked to the major histocompatibility complex (MHC), have been
implicated in atopic asthma. Asthma is highly prevalent in the Venezuelan population …

Background Allergic bronchopulmonary aspergillosis occurs in 7–10% of cystic fibrosis (CF)
and 1–2% of asthmatic patients. HLA-DR restriction and increased sensitivity to IL-4 …