[HTML][HTML] A review and perspective on hybrid modelling methodologies

AM Schweidtmann, D Zhang, M von Stosch - Digital Chemical Engineering, 2023 - Elsevier
The term hybrid modeling refers to the combination of parametric models (typically derived
from knowledge about the system) and nonparametric models (typically deduced from data) …

The rise of scientific machine learning: a perspective on combining mechanistic modelling with machine learning for systems biology

B Noordijk, ML Garcia Gomez… - Frontiers in Systems …, 2024 - frontiersin.org
Both machine learning and mechanistic modelling approaches have been used
independently with great success in systems biology. Machine learning excels in deriving …

Discovering dynamics and parameters of nonlinear oscillatory and chaotic systems from partial observations

G Stepaniants, AD Hastewell, DJ Skinner, JF Totz… - Physical Review …, 2024 - APS
Despite rapid progress in data acquisition techniques, many complex physical, chemical,
and biological systems remain only partially observable, thus posing the challenge to …

Generalized Inverse Optimal Control and its Application in Biology

JR Banga, S Sager - arXiv preprint arXiv:2405.20747, 2024 - arxiv.org
Living organisms exhibit remarkable adaptations across all scales, from molecules to
ecosystems. We believe that many of these adaptations correspond to optimal solutions …

Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling

A Rahimabadi, H Benali - bioRxiv, 2024 - biorxiv.org
Parameterization and a priori identifiability analysis are two interconnected steps that should
be carried out in advance of model calibration. In the first place, we propose a framework for …

Inference from Limited Observations in Statistical, Dynamical, and Functional Problems

G Stepaniants - 2024 - dspace.mit.edu
Observational data in physics and the life sciences comes in many varieties. Broadly, we
can divide datasets into cross-sectional data which record a set of observations at a given …

[PDF][PDF] Digital Chemical Engineering

The term hybrid modeling refers to the combination of parametric models (typically derived
from knowledge about the system) and nonparametric models (typically deduced from data) …