Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …

There are two branches in boron medicinal chemistry: the first focuses on single boron atom
compounds, and the second utilizes boron clusters. Boron clusters and their heteroatom …

What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …

Boron, in the form of boric acid, has played a role in medicine as a mild antiseptic and an
eye wash since its preparation from borax in the 18th century. However, the use of boron in …

This review focuses on the current status and perspectives of the application of polyhedral
boron hydrides in medicine. The main topics discussed are boron neutron capture therapy …

Proteolytic processing of viral polyproteins is essential for retrovirus infectivity. Retroviral
proteases (PR) become activated during or after assembly of the immature, non-infectious …

Cobalt bisdicarbollides (COSANs) are inorganic boron-based anions that have been
previously reported to permeate by themselves through lipid bilayer membranes, a …

Inorganic complexes are versatile platforms for the development of potent and selective
pharmaceutical agents. Cobalt possesses a diverse array of properties that can be …

Antiviral inhibitors of HIV-1 protease are a notable success of structure-based drug design
and have dramatically improved AIDS therapy. Analysis of the structures and activities of …

The tremendous challenge presented by the specific molecular recognition of single
biomacromolecular targets within complex biological systems demands novel and creative …