The neural basis of timing: distributed mechanisms for diverse functions

JJ Paton, DV Buonomano - Neuron, 2018 - cell.com
Timing is critical to most forms of learning, behavior, and sensory-motor processing.
Converging evidence supports the notion that, precisely because of its importance across a …

The neural bases for timing of durations

A Tsao, SA Yousefzadeh, WH Meck… - Nature reviews …, 2022 - nature.com
Durations are defined by a beginning and an end, and a major distinction is drawn between
durations that start in the present and end in the future ('prospective timing') and durations …

[HTML][HTML] Toward an integration of deep learning and neuroscience

AH Marblestone, G Wayne, KP Kording - Frontiers in computational …, 2016 - frontiersin.org
Neuroscience has focused on the detailed implementation of computation, studying neural
codes, dynamics and circuits. In machine learning, however, artificial neural networks tend …

Flexible timing by temporal scaling of cortical responses

J Wang, D Narain, EA Hosseini, M Jazayeri - Nature neuroscience, 2018 - nature.com
Musicians can perform at different tempos, speakers can control the cadence of their
speech, and children can flexibly vary their temporal expectations of events. To understand …

What is memory? The present state of the engram

M Poo, M Pignatelli, TJ Ryan, S Tonegawa… - BMC biology, 2016 - Springer
The mechanism of memory remains one of the great unsolved problems of biology.
Grappling with the question more than a hundred years ago, the German zoologist Richard …

Bayesian computation through cortical latent dynamics

H Sohn, D Narain, N Meirhaeghe, M Jazayeri - Neuron, 2019 - cell.com
Statistical regularities in the environment create prior beliefs that we rely on to optimize our
behavior when sensory information is uncertain. Bayesian theory formalizes how prior …

Flexible sensorimotor computations through rapid reconfiguration of cortical dynamics

ED Remington, D Narain, EA Hosseini, M Jazayeri - Neuron, 2018 - cell.com
Neural mechanisms that support flexible sensorimotor computations are not well
understood. In a dynamical system whose state is determined by interactions among …

Low-dimensional dynamics for working memory and time encoding

CJ Cueva, A Saez, E Marcos… - Proceedings of the …, 2020 - National Acad Sciences
Our decisions often depend on multiple sensory experiences separated by time delays. The
brain can remember these experiences and, simultaneously, estimate the timing between …

Striatal dynamics explain duration judgments

TS Gouvêa, T Monteiro, A Motiwala, S Soares… - Elife, 2015 - elifesciences.org
The striatum is an input structure of the basal ganglia implicated in several time-dependent
functions including reinforcement learning, decision making, and interval timing. To …

Differential encoding of time by prefrontal and striatal network dynamics

KI Bakhurin, V Goudar, JL Shobe, LD Claar… - Journal of …, 2017 - Soc Neuroscience
Telling time is fundamental to many forms of learning and behavior, including the
anticipation of rewarding events. Although the neural mechanisms underlying timing remain …