Neglected scrub typhus: an updated review with a focus on omics technologies

D Sharma, A Sharma, B Singh, S Kumar… - Asian Pacific Journal …, 2022 - journals.lww.com
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-
Pacific region. The disease is caused by an obligate intracellular bacteria Orientia …

Polymerase Spiral Reaction (PSR) as a point-of-care diagnostic assay: A systematic review

R Dixit, NK Kodali, M Biswal, JAJ Prakash… - Expert Review of …, 2024 - Taylor & Francis
Introduction The current systematic review aimed to collect and analyze the comprehensive
evidence regarding Polymerase Spiral Reaction (PSR) and to estimate its diagnostic …

Phylogenetic and immunological investigations of complete TSA56 ORF of Orientia tsutsugamushi present in acute encephalitis syndrome cases from eastern Uttar …

P Bhardwaj, SP Behera, N Nanaware, K Zaman… - Archives of …, 2023 - Springer
Scrub typhus (ST) caused by Orientia tsutsugamushi (OT), has long been known to cause
acute encephalitis syndrome (AES) and acute febrile illness (AFI). The immunodominant 56 …

Deciphering the Genotypic Diversity and Epidemiology of Scrub Typhus Genotypes in India: A Systematic Review and Meta-Analysis

RK Nema, AK Singh, D Raj, P Gupta, RR Tiwari… - Microbial …, 2024 - Elsevier
Background Scrub typhus is a significant cause of Acute Febrile Illness in India and presents
a range of clinical manifestations influenced by the genotypes of the causative agent …

CRISPR/Cas12a-Based Detection Platform for Early and Rapid Diagnosis of Scrub Typhus

P Bhardwaj, NS Nanaware, SP Behera, S Kulkarni… - Biosensors, 2023 - mdpi.com
Orientia tsutsugamushi is responsible for causing scrub typhus (ST) and is the leading
cause of acute encephalitis syndrome (AES) in AES patients. A rapid and sensitive method …

Genotypic Characterization of Orientia tsutsugamushi Isolated From Acute Encephalitis Syndrome and Acute Febrile Illness Cases in the Gorakhpur Area, Uttar …

N Nanaware, D Desai, A Banerjee, K Zaman… - Frontiers in …, 2022 - frontiersin.org
Scrub typhus infections caused by Orientiatsutsugamushi (OT), continue to remain
underdiagnosed globally, due to the lack of distinctive symptoms. The elusive nature of the …

Clinical, laboratory profile and molecular characterization of Orientia tsutsugamushi among fatal scrub typhus patients from Karnataka, India

K Chunduru, M A. R, S Poornima, M Hande H… - Infectious …, 2024 - Taylor & Francis
Background Scrub typhus is a vector-borne infection caused by the obligate intracellular
organism Orientia tsutsugamushi. In some cases, scrub typhus can result in severe …

Molecular detection of spotted fever group of Rickettsiae in acute encephalitis syndrome cases from eastern Uttar Pradesh region of India

SP Behera, R Singh, H Deval… - Zoonoses and Public …, 2023 - Wiley Online Library
Abstract The Eastern Uttar Pradesh region of India is known for its endemicity of acute
encephalitis syndrome (AES). Decades of research have established that Orientia …

Integration of IgM ELISA and 56ákDa gene PCR in management of pediatric acute encephalitis syndrome associated with scrub typhus

P Bhardwaj, V Yadav, A Sharma, S Gulafshan… - Infectious Diseases …, 2024 - Elsevier
Objectives To identify the potential target genes for detection of Orientia tsutsugamushi (OT)
in pediatric acute encephalitis syndrome (pAES). Methods DNA was extracted from whole …

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P Bhardwaj, V Yadav, A Sharma, S Gulafshan… - researchgate.net
Objectives: To identify the potential target genes for detection of Orientia tsutsugamushi (OT)
in pediatric acute encephalitis syndrome (pAES). Methods: DNA was extracted from whole …