Apical constriction is a cell shape change that promotes tissue remodeling in a variety of
homeostatic and developmental contexts, including gastrulation in many organisms and …

Primary cilia are microtubule-based organelles that extend from the apical surface of most
mammalian cells, forming when the basal body (derived from the mother centriole) docks at …

Introduction In vivo imaging provides a window into the spatially complex, rapidly evolving
physiology of the cell that structural imaging alone cannot. However, observing this …

Large, living biological specimens present challenges to existing optical imaging techniques
because of their absorptive and scattering properties. We developed selective plane …

Live imaging of the actin cytoskeleton is crucial for the study of many fundamental biological
processes, but current approaches to visualize actin have several limitations. Here we …

Apical constriction facilitates epithelial sheet bending and invagination during
morphogenesis,. Apical constriction is conventionally thought to be driven by the continuous …

The molecular and cellular bases of cell shape change and movement during
morphogenesis and wound healing are of intense interest and are only beginning to be …

Actin filaments (F‐actin) are protein polymers that undergo rapid assembly and disassembly
and control an enormous variety of cellular processes ranging from force production to …

Abstract The small GTPase Rac induces actin polymerization, membrane ruffling and focal
contact formation in cultured single cells but can either repress or stimulate motility in …

The C‐terminus of mouse talin (amino acids 2345–2541) is responsible for all of the
protein'sf‐actin binding capacity. Unlike full‐length talin, the C‐terminal f‐actin binding …