Cell–extracellular matrix mechanotransduction in 3D
A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …
including differentiation, migration and proliferation, through mechanotransduction. Studies …
Unravelling cell migration: defining movement from the cell surface
F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Cell Trafficking at the Intersection of the Tumor–Immune Compartments
Migration is an essential cellular process that regulates human organ development and
homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell …
homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell …
Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells
Particulate matter (PM) is a ubiquitous component of air pollution that is epidemiologically
linked to human pulmonary diseases. PM chemical composition varies widely, and the …
linked to human pulmonary diseases. PM chemical composition varies widely, and the …
Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors
AC Johnston, GM Alicea, CC Lee, PV Patel… - BioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Chimeric antigen receptor (CAR) T cells express antigen-specific synthetic receptors, which
upon binding to cancer cells, elicit T cell anti-tumor responses. CAR T cell therapy has …
upon binding to cancer cells, elicit T cell anti-tumor responses. CAR T cell therapy has …
Aberrant migration features in primary skin fibroblasts of Huntington's disease patients hold potential for unraveling disease progression using an image based …
S Gharaba, A Shalem, O Paz, N Muchtar, L Wolf… - Computers in Biology …, 2024 - Elsevier
Huntington's disease (HD) is a complex neurodegenerative disorder with considerable
heterogeneity in clinical manifestations. While CAG repeat length is a known predictor of …
heterogeneity in clinical manifestations. While CAG repeat length is a known predictor of …
Targeted therapeutics delivery by exploiting biophysical properties of senescent cells
Cellular senescence refers to a state of irreversible arrest of cell proliferation in response to
various forms of cellular stress. It is known that the accumulation of senescent cells is a …
various forms of cellular stress. It is known that the accumulation of senescent cells is a …
Profiling Dynamic Patterns of Single‐Cell Motility
Cell motility plays an essential role in many biological processes as cells move and interact
within their local microenvironments. Current methods for quantifying cell motility typically …
within their local microenvironments. Current methods for quantifying cell motility typically …
[PDF][PDF] Random walk generation and classification within an online learning platform.
Advancements in technology have introduced new approaches in teaching and learning
processes. Machine learning algorithms analyse and recognize patterns of data and …
processes. Machine learning algorithms analyse and recognize patterns of data and …
Profiling dynamic patterns of single-cell motility
Cell motility plays an essential role in many biological processes as cells move and interact
within their local microenvironments. Current methods for quantifying cell motility typically …
within their local microenvironments. Current methods for quantifying cell motility typically …