Antimicrobial peptides as anticancer agents: functional properties and biological activities
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …
An update on cell-penetrating peptides with intracellular organelle targeting
CP Cerrato, Ü Langel - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Cell-penetrating peptide (CPP) technologies represent an important strategy to
address drug delivery to specific intracellular compartments by covalent conjugation to …
address drug delivery to specific intracellular compartments by covalent conjugation to …
Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …
[HTML][HTML] AdipoRon Alleviates Liver Injury by Protecting Hepatocytes from Mitochondrial Damage Caused by Ionizing Radiation
Y Liu, Y Xu, H Ji, F Gao, R Ge, D Zhou, H Fu… - International Journal of …, 2024 - mdpi.com
Radiation liver injury is a common complication of hepatocellular carcinoma radiotherapy. It
is mainly caused by irreversible damage to the DNA of hepatocellular cells directly by …
is mainly caused by irreversible damage to the DNA of hepatocellular cells directly by …
Peptide-based strategies for overcoming multidrug-resistance in cancer therapy
X Luo, Y Wu, X Zhang, M Tang, F Ju, Z Qin… - Chinese Chemical …, 2024 - Elsevier
Despite ongoing advancements in cancer treatment, the emergence of primary and acquired
resistance poses a significant challenge for both traditional chemotherapy and immune …
resistance poses a significant challenge for both traditional chemotherapy and immune …
A novel CD47-blocking peptide fused to pro-apoptotic KLA repeat inhibits lung cancer growth in mice
L Pan, L Hu, M Chen, Y Song, Z Chen, Y Gu… - Cancer Immunology …, 2023 - Springer
CD47 is highly expressed in many tumor tissues and induces immune evasion by interaction
with SIRP-alpha (signal regulatory protein-alpha) expressed on tumor-associated …
with SIRP-alpha (signal regulatory protein-alpha) expressed on tumor-associated …
Bioactive peptides from food science to pharmaceutical industries: Their mechanism of action, potential role in cancer treatment and available resources
M Bidram, MR Ganjalikhany - Heliyon, 2024 - cell.com
Cancer is known as the main cause of mortality in the world, and every year, the rate of
incidence and death due to cancer is increasing. Bioactive peptides are one of the novel …
incidence and death due to cancer is increasing. Bioactive peptides are one of the novel …
Targeting Specific Barriers
Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
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Therapeutic peptides in anticancer therapy
Peptide-based therapeutics conjugated with various nanomaterials or bioactives have
shown promising effects in anticancer therapy and thus has evolved as emerging anticancer …
shown promising effects in anticancer therapy and thus has evolved as emerging anticancer …