Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …
disease in incidence. Despite significant worldwide investment in research, cancer remains …
[HTML][HTML] Influencing factors and strategies of enhancing nanoparticles into tumors in vivo
M Zhang, S Gao, D Yang, Y Fang, X Lin, X Jin… - … Pharmaceutica Sinica B, 2021 - Elsevier
The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …
A holistic approach to targeting disease with polymeric nanoparticles
CJ Cheng, GT Tietjen, JK Saucier-Sawyer… - Nature reviews Drug …, 2015 - nature.com
The primary goal of nanomedicine is to improve clinical outcomes. To this end, targeted
nanoparticles are engineered to reduce non-productive distribution while improving …
nanoparticles are engineered to reduce non-productive distribution while improving …
Recent advances in nanostrategies capable of overcoming biological barriers for tumor management
Engineered nanomaterials have been extensively employed as therapeutics for tumor
management. Meanwhile, the complex tumor niche along with multiple barriers at the …
management. Meanwhile, the complex tumor niche along with multiple barriers at the …
Stromal barriers and strategies for the delivery of nanomedicine to desmoplastic tumors
Nanoparticle based delivery formulations have become a leading delivery strategy for
cancer imaging and therapy. The success of nanoparticle-based therapy relies heavily on …
cancer imaging and therapy. The success of nanoparticle-based therapy relies heavily on …
Tumor microenvironment targeted nanotherapy
C Fernandes, D Suares, MC Yergeri - Frontiers in pharmacology, 2018 - frontiersin.org
Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …
Heat-generating iron oxide nanocubes: Subtle “destructurators” of the tumoral microenvironment
Several studies propose nanoparticles for tumor treatment, yet little is known about the fate
of nanoparticles and intimate interactions with the heterogeneous and ever-evolving tumor …
of nanoparticles and intimate interactions with the heterogeneous and ever-evolving tumor …
[HTML][HTML] Current approaches for improving intratumoral accumulation and distribution of nanomedicines
The ability of nanoparticles and macromolecules to passively accumulate in solid tumors
and enhance therapeutic effects in comparison with conventional anticancer agents has …
and enhance therapeutic effects in comparison with conventional anticancer agents has …
Toward predicting nanoparticle distribution in heterogeneous tumor tissues
Nanobio interaction studies have generated a significant amount of data. An important next
step is to organize the data and design computational techniques to analyze the nanobio …
step is to organize the data and design computational techniques to analyze the nanobio …
Strategies for delivering nanoparticles across tumor blood vessels
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …