Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

Pain disrupts sleep, and sleep deprivation or interference can alter pain perception in
animals and humans, for example by increasing sensitivity to pain. However, the mechanism …

New evidence is emerging about the dynamics of interaction between circadian rhythms and
brain waves, whose coordination occurs through the entrainment process. The so-called" …

Tumor necrosis factor α (TNFα), a cytokine mainly secreted by active macrophages and
monocytes, causes hemorrhagic necrosis of tumor tissues, kills tumor cells, regulates …

Objective: To explore the active components and mechanism of Jiaotai Pill (JTP) in the
treatment of primary insomnia (PI) based on gene expression omnibus. Methods: The main …

Human induced pluripotent stem cells (hiPSCs) derived into neurons offer a powerful in vitro
model to study cellular processes. One method to characterize functional network properties …

背景慢性失眠是老年人群常见的疾病之一, 常伴有不同程度的认知功能损害,
严重影响老年人生活质量, 而关于老年慢性失眠患者认知功能损害的生物学机制尚不明确 …

背景童年经历对中老年健康的影响已成为研究热点, 但其对中老年认知功能的影响效应及路径尚
不明确. 目的从全生命周期视角分析童年社会经济地位对中老年认知功能的影响 …

睡眠障碍是常见的精神障碍之一, 其发病机制不明确, 目前尚无生物学标志物可以预测睡眠障碍
的发病及评估睡眠障碍的严重程度. 维生素D 缺乏可能影响睡眠状态. 本文对维生素D …

Herein the major accomplishments, trials and tribulations, and epiphanies experienced by
James M. Krueger over the course of his career in sleep research are presented. They …