A major limitation of organ allotransplantation is the insufficient supply of donor organs.
Consequently, thousands of patients die every year while waiting for a transplant. Progress …

The increasing life expectancy of humans has led to a growing numbers of patients with
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …

Background Cross-species immunological incompatibilities have hampered pig-to-human
xenotransplantation, but porcine genome engineering recently enabled the first successful …

Xenotransplantation research has made considerable progress in recent years, largely
through the increasing availability of pigs with multiple genetic modifications. We suggest …

The success of organ transplantation is limited by the complications of immunosuppression,
by chronic rejection, and by the insufficient organ supply, and thousands of patients die …

The growing shortage of available organs is a major problem in transplantology. Thus, new
and alternative sources of organs need to be found. One promising solution could be …

Transplantable Tissue—Immune and Genome Engineering Dramatic advancements in the
use of synthetic and mechanical devices to replace tissues have been made, but restoring …

First pig-to-human heart transplantation: The Innovation Skip to Main Content
Advertisement The Innovation All content is freely available to readers and supported …

Half a million patients in the USA alone require treatment for burns annually. Following an
extensive burn, it may not be possible to provide sufficient autografts in a single setting. Pig …

Xenotransplantation: past, present, and future : Current Opinion in Organ Transplantation
Xenotransplantation: past, present, and future : Current Opinion in Organ Transplantation Log in …