Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

SA Bonini, M Premoli, S Tambaro, A Kumar… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …

Minor cannabinoids: biosynthesis, molecular pharmacology and potential therapeutic uses

KB Walsh, AE McKinney, AE Holmes - Frontiers in Pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Cannabidiol: State of the art and new challenges for therapeutic applications

S Pisanti, AM Malfitano, E Ciaglia, A Lamberti… - Pharmacology & …, 2017 - Elsevier
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The pharmacological case for cannabigerol

R Nachnani, WM Raup-Konsavage, KE Vrana - Journal of Pharmacology …, 2021 - ASPET
Medical cannabis and individual cannabinoids, such as Δ9-tetrahydrocannabinol (Δ9-THC)
and cannabidiol (CBD), are receiving growing attention in both the media and the scientific …

The phytochemical diversity of commercial Cannabis in the United States

CJ Smith, D Vergara, B Keegan, N Jikomes - PLoS one, 2022 - journals.plos.org
The legal status of Cannabis is changing, fueling an increasing diversity of Cannabis-
derived products. Because Cannabis contains dozens of chemical compounds with potential …

Appraising the “entourage effect”: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer

S Blasco-Benito, M Seijo-Vila, M Caro-Villalobos… - Biochemical …, 2018 - Elsevier
Breast cancer is the second leading cause of death among women. Although early
diagnosis and development of new treatments have improved their prognosis, many patients …

Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …